Millipore Sigma Vibrant Logo

14-510M Lyn Protein, active, 250 µg

View Products on Sigmaaldrich.com
14-510M
250 µg  Also available in 10 μg size (cat#14-510) and in bulk (cat# 14-510-K).
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Fulfillment and delivery delayed
Fulfillment and delivery delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information
      Description
      Catalogue Number14-510M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionLyn Protein, active, 250 µg
      OverviewN-terminal his6-tagged recombinant full-length human Lyn
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal his6-tagged recombinant full-length human Lyn, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Application NotesKinase Assays: Depending upon the specific activity of the lot , 7.6 -15.3ng of enzyme phosphorylated 0.1 mg/ml poly (Glu, Tyr) 4:1 {Sigma P7244} in a standard kinase assay. See technical datasheet included with purchased product for lot specific activity values.
      Biological Information
      Sourceexpressed in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • LYN
      • JTK8
      • FLJ26625
      Protein TargetLyn
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummarySIZE: 512 amino acids; 58574 Da
      SUBUNIT: Interacts with phosphorylated LIME1 and with CD79A upon BCR activation. Interacts with Epstein-Barr virus LMP2A. Interacts with TGFB1I1.
      TISSUE SPECIFICITY: Expressed in primary neuroblastoma tumors.
      SIMILARITY: SwissProt: P07948 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
      Molecular Weight59.6kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-510) and in bulk (cat# 14-510-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-510M 04053252270796

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      14-510 Lyn Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases