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CC065 Human Tenascin-C Purified Protein

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CC065
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Key Applications
      PC, CULT
      Description
      Catalogue NumberCC065
      ReplacesCC066
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionHuman Tenascin-C Purified Protein
      OverviewPurified Human Tenascin-C Protien. Tenascin is known to: 1) play an active role in development of central nervous system and mesenchymal-derived organs; 2) exist in vasculature of tumors in adults; and 3) function in cell adhesion. By SDS-PAGE analysis, the protein migrates around 280-300kD.
      Alternate Names
      • TN-C
      • Tenascin
      • Hexabrachion
      • Cytotactin
      • Neuronectin
      References
      Product Information
      HS Code3502 90 90
      PresentationPurified protein supplied as a liquid in PBS containing no preservatives.
      Quality LevelMQ100
      Applications
      Key Applications
      • Positive Control
      • Cell Culture
      Application NotesCell adhesion assays.

      Optimal working dilutions must be determined by end user.
      Biological Information
      Concentration0.1 mg/mL
      Purity> 97% pure by SDS-PAGE
      SourceHuman glioma cell line (U251).
      Entrez Gene Number
      Gene Symbol
      • TNC
      • Hexabrachion
      • HXB
      • GMEM
      • TN
      • Neuronectin
      • Tenascin-C
      • MGC167029
      • JI
      • TN-C
      • Cytotactin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P24821 # Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
      SIZE: 2201 amino acids; 240866 Da
      SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
      SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
      PTM: N-glycosylated (By similarity).
      SIMILARITY: SwissProt: P24821 ## Belongs to the tenascin family. & Contains 15 EGF-like domains. & Contains 1 fibrinogen C-terminal domain. & Contains 15 fibronectin type-III domains.
      Stem Cell Type
      • Human Embryonic Stem Cells
      • Mesenchymal Stem Cells
      • Neural Stem Cells
      • Hematopoietic Stem Cells
      • Epithelial Cells
      • Pancreatic Stem Cells
      • Induced Pluripotent Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70ºC for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      CC065 04053252671982

      Documentation

      Human Tenascin-C Purified Protein SDS

      Title

      Safety Data Sheet (SDS) 

      Human Tenascin-C Purified Protein Certificates of Analysis

      TitleLot Number
      HUMAN TENASCIN - C 2483223
      HUMAN TENASCIN - C PURIFIED PROTEIN - 2137988 2137988
      HUMAN TENASCIN - C PURIFIED PROTEIN - 2375504 2375504
      HUMAN TENASCIN - C PURIFIED PROTEIN - 2390408 2390408
      HUMAN TENASCIN - C PURIFIED PROTEIN - 2426461 2426461
      HUMAN TENASCIN - C PURIFIED PROTEIN - 2450673 2450673
      HUMAN TENASCIN - C - 3209134 3209134
      HUMAN TENASCIN - C - 3243036 3243036
      HUMAN TENASCIN - C - 3243037 3243037
      HUMAN TENASCIN - C - 3305886 3305886

      Data Sheet

      Title
      HUMAN TENASCIN - C PURIFIED PROTEIN