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ABC213 Anti-phospho ULK1 Antibody (Ser777)

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ABC213
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, PIARbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC213
      DescriptionAnti-phospho ULK1 Antibody (Ser777)
      Alternate Names
      • Serine/threonine-protein kinase ULK1
      • Serine/threonine-protein kinase Unc51.1
      • Unc-51-like kinase 1
      Background InformationULK1 or autophagy-related protein 1 homolog (ATG1) is a serine/threonine protein kinase. It is a ubiquitously expressed protein that is highly abundant in the brain, skeletal muscle, and heart. It is involved in the signaling pathway of mTOR receptors leading to the regulation of autophagy in nutrient-deprived cells. mTOR may interact with ULK1 as a complex of ULK1/FIP200/Atg13. ULK1 may play an important role in neuronal development: Elimination of ULK1's enzymatic activity by targeted disruption of its kinase domain has blocked the outgrowth of neurons in the developing mouse brain, possibly by blocking the ULK1-mediated trafficking of neurotrophins.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-phospho ULK1 Antibody (Ser777) is a highly specific rabbit polyclonal antibody, that targets Autophagy-related protein & has been tested in western blotting & Peptide Inhibition Assay.
      Key Applications
      • Western Blotting
      • Peptide Inhibition Assay
      Application NotesEvaluated by Western Blotting/Peptide Inhibition Analysis in A431 cell lysate.

      Western Blotting/Peptide Inhibition Analysis: 2 µg/mL of this antibody detected phospho ULK1 (Ser777) in 10 µg of A431 cell lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to a region near the C-terminus of human ULK1 phosphorylated at Ser777.
      EpitopeNear C-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Ulk1
      Modifications
      • Phosphorylation
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~120 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected phospho ULK1 (Ser777) in 10 µg of A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC213 04053252941191

      Documentation

      Anti-phospho ULK1 Antibody (Ser777) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-phospho ULK1 Antibody (Ser777) Certificates of Analysis

      TitleLot Number
      Anti-phospho ULK1 (Ser777) 3082498
      Anti-phospho ULK1 (Ser777) - 3208807 3208807
      Anti-phospho ULK1 (Ser777) - 3506611 3506611
      Anti-phospho ULK1 (Ser777) - 3524849 3524849
      Anti-phospho ULK1 (Ser777) - 4031408 4031408
      Anti-phospho ULK1 (Ser777) - Q2343007 Q2343007
      Anti-phospho ULK1 (Ser777) -2603419 2603419
      Anti-phospho ULK1 (Ser777) -2686105 2686105
      Anti-phospho ULK1 (Ser777) Polyclonal Antibody 2943775
      Anti-phospho ULK1 (Ser777) Polyclonal Antibody 2865442

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies