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ABS192 Anti-phospho-SRPK2 (Ser497) Antibody

Anti-phospho-SRPK2 (Ser497) Antibody is a highly specific rabbit polyclonal antibody, that targets SRPK & has been tested in western blotting.

Anti-phospho-SRPK2 (Ser497) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: SRPK2 UniProt Number: P78362
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ABS192
200 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, HtWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS192
      DescriptionAnti-phospho-SRPK2 (Ser497) Antibody
      Alternate Names
      • SRSF protein kinase 2
      • SFRS protein kinase 2
      • Serine/arginine-rich protein-specific kinase 2
      • SR-protein-specific kinase 2
      • SRSF protein kinase 2 N-terminal
      • SRSF protein kinase 2 C-terminal
      Background InformationSRPK2 is also known as SRSF protein kinase 2, SFRS protein kinase 2, and Serine/arginine-rich protein-specific kinase 2. SRPK2 is a kinase which is involved in the phosphorylation of SR splicing factors, and the regulation of splicing. SRPK2 also promotes neuronal apoptosis, plays an essential role in splicesomal B complex formation, and mediates hepatitis B virus (HBV) replication and core protein phosphorylation. SRPK2 is highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.
      References
      Product Information
      FormatAffinity Purified
      Control
      • NIH3T3 cell lysate and Insulin treated NIH3T3 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-phospho-SRPK2 (Ser497) Antibody is a highly specific rabbit polyclonal antibody, that targets SRPK & has been tested in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the protein kinase domain of human SRPK2 (Ser497).
      EpitopeProtein kinase domain
      HostRabbit
      SpecificityThis antibody recognizes the protein kinase domain of SRPK2 phosphorylated at Ser497.
      Species Reactivity
      • Human
      • Mouse
      • Hamster
      Species Reactivity NoteDemonstrated to react with Mouse, Hamster, and Human. Predicted to react with Rat and Xenopus based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SRPK2
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~120 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing at ~77 kDa and ~79 kDa. Uniprot states 8 phosphorylation sites are known to exist.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in NIH3T3 cell lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected SRPK2 (Ser497) in 10 µg of NIH3T3 cell lysate and Insulin treated NIH3T3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS192 04053252861499

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies