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AP1159 Anti-TNFRSF14 Mouse mAb (2G6-2C7)

Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Pricing & Availability

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AP1159-100UG
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      100 μg
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      Description
      OverviewRecognizes the TNFRSF14 protein in human pancreatic cancer tissue.
      Catalogue NumberAP1159
      Brand Family Calbiochem®
      SynonymsAnti-Tumor Necrosis Factor Receptor Super family 14
      Application Data
      Detection of human TNFRSF14 by immunoblotting. Sample: Whole cell lysate from 293T cells, transfected with full-length, recombinant, human TNFRSF14 (lane 1) and from non-transfected 293T cells (lane 2). Primary antibody: Anti-TNFRSF14 Mouse mAb (2G6-2C7) (Cat. No. AP1159) (1-5 µg/ml). Detection: Chemiluminescence.

      Detection of human TNFRSF14 by staining paraffin sections. Sample: Formalin-fixed, paraffin-embedded human pancreatic cancer tissue. Primary antibody: Anti-TNFRSF14 Mouse mAb (2G6-2C7) (Cat. No. AP1159) (1 µg/ml). Detection: coloritmetric (DAB).
      References
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Negative control293T cells
      Positive controlHuman pancreatic cancer tissue
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Immunoblotting (Western Blotting)
      Paraffin Sections
      Application NotesELISA (see comments)
      Immunoblotting (1-5 µg)
      Paraffin Sections (1 µg/ml)
      Application CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      ImmunogenFull-length, recombinant, human TNFRSF14 (aa 38-248), expressed as a GST fusion protein
      Clone2G6-2C7
      HostMouse
      IsotypeIgG₁
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Regulatory Review
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AP1159-100UG 04055977212655

      Documentation

      Anti-TNFRSF14 Mouse mAb (2G6-2C7) SDS

      Title

      Safety Data Sheet (SDS) 

      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-October-2010 RFH
      SynonymsAnti-Tumor Necrosis Factor Receptor Super family 14
      ApplicationELISA (see comments)
      Immunoblotting (1-5 µg)
      Paraffin Sections (1 µg/ml)
      Application Data
      Detection of human TNFRSF14 by immunoblotting. Sample: Whole cell lysate from 293T cells, transfected with full-length, recombinant, human TNFRSF14 (lane 1) and from non-transfected 293T cells (lane 2). Primary antibody: Anti-TNFRSF14 Mouse mAb (2G6-2C7) (Cat. No. AP1159) (1-5 µg/ml). Detection: Chemiluminescence.

      Detection of human TNFRSF14 by staining paraffin sections. Sample: Formalin-fixed, paraffin-embedded human pancreatic cancer tissue. Primary antibody: Anti-TNFRSF14 Mouse mAb (2G6-2C7) (Cat. No. AP1159) (1 µg/ml). Detection: coloritmetric (DAB).
      DescriptionPurified mouse monoclonal antibody. Recognizes the TNFRSF14 protein.
      BackgroundTNFRSF14 is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.
      HostMouse
      ImmunogenFull-length, recombinant, human TNFRSF14 (aa 38-248), expressed as a GST fusion protein
      Clone2G6-2C7
      IsotypeIgG₁
      Specieshuman
      Positive controlHuman pancreatic cancer tissue
      Negative control293T cells
      FormLiquid
      FormulationIn PBS, pH 7.2.
      PreservativeNone
      CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Regulatory Review