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AB9279 Anti-Rhodopsin Antibody

Anti-Rhodopsin Antibody detects level of Rhodopsin & has been published & validated for use in IH(P).

Anti-Rhodopsin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Sensory & PNS Gene Symbol: RHO, RP4, rhodopsin, MGC138311, Opsin-2, OPN2, MGC138309, Rhodopsin UniProt Number: P08100
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AB9279
50 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9279
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Rhodopsin Antibody
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Liquid in PBS, with less than 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Rhodopsin Antibody detects level of Rhodopsin & has been published & validated for use in IH(P).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on paraffin embedded tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the 2nd extracellular domain of human Rhodopsin.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Rhodopsin.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryRetinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
      Gene Symbol
      • RHO
      • RP4
      • rhodopsin
      • MGC138311
      • Opsin-2
      • OPN2
      • MGC138309
      • Rhodopsin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P08100 # Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
      SIZE: 348 amino acids; 38893 Da
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Rod shaped photoreceptor cells which mediates vision in dim light.
      PTM: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
      DISEASE: SwissProt: P08100 # Defects in RHO are the cause of retinitis pigmentosa type 4 (RP4) [MIM:180380]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP4 inheritance is autosomal dominant. & Defects in RHO are a cause of retinitis pigmentosa autosomal recessive (ARRP) [MIM:268000]. & Defects in RHO are a cause of autosomal dominant congenital stationary night blindness 1 (CSNBAD1) [MIM:610445]; also known as rhodopsin-related congenital stationary night blindness. Congenital stationary night blindness is a nonprogressive retinal disorder characterized by impaired night vision and ocular symptoms such as myopia, hyperopia, nystagmus and reduced visual acuity.
      SIMILARITY: SwissProt: P08100 ## Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9279 04053252269899

      Documentation

      Anti-Rhodopsin Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Rhodopsin Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI- RHODOPSIN - 2538631 2538631
      RABBIT ANTI- RHODOPSIN - 3199166 3199166
      RABBIT ANTI- RHODOPSIN - 3442513 3442513
      RABBIT ANTI- RHODOPSIN - 3519308 3519308
      RABBIT ANTI- RHODOPSIN - 3677711 3677711
      RABBIT ANTI- RHODOPSIN - 3992241 3992241
      RABBIT ANTI- RHODOPSIN - 4085560 4085560
      RABBIT ANTI- RHODOPSIN - 4124271 4124271
      RABBIT ANTI- RHODOPSIN - 4169249 4169249
      RABBIT ANTI- RHODOPSIN - 4187710 4187710
      Show more

      Data Sheet

      Title
      RABBIT ANTI- RHODOPSIN AFFINITY PURIFIED

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies