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MABC550 Anti-Pex3 Antibody, clone 14F3.2

MABC550
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC550
      DescriptionAnti-Pex3 Antibody, clone 14F3.2
      Alternate Names
      • Pex3
      • Peroxisomal biogenesis factor 3
      • Peroxin-3
      • Peroxisomal assembly protein PEX3
      Background InformationPex3 (also known as peroxin-3, peroxisomal assembly protein PEX3, peroxisomal biogenesis factor 3, transformation-related protein 18) is a multitransmembrane peroxisome protein that is encoded by the PEX3 gene in human (also known as PBD10A and TRG18). Pex19 is involved in maintaining peroxisome biosynthesis and integrity by acting as a docking factor for pex19 and, together with other peroxins (PEXs), is essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs), including Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP), are lethal diseases characterized by multiple defects in peroxisome function, resulting in failure of importing one or more classes of peroxisomal matrix proteins into the organelle.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Pex3 Antibody, clone 14F3.2 is an antibody against Pex3 for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50-1,000 dilution from a representative lot detected Pex3 in human liver and human kidney tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Pex3.
      Clone14F3.2
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG2bκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PEX3
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~40 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pex3 in 10 µg of HepG2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC550 04055977159271