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MABD90 Anti-HLA-DRB1 Antibody, clone DJ9

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MABD90
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, IHC, FCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABD90
      DescriptionAnti-HLA-DRB1 Antibody, clone DJ9
      Alternate Names
      • Major histocompatibility complex, class II
      • DRB1
      • DRB1
      Background InformationHLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. HLA-DRB1 binds peptides derived from antigens that access the endocytic route of antigen presenting cells and presents them on the cell surface for recognition by the CD4 T-cells. Class II molecules are expressed in antigen presenting cells B lymphocytes, dendritic cells, macrophages. HLA-Drb1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. HLA-DRB1, clone DJ9, has been shown to be a relevant marker of bone marrow derived mesenchymal stem cells and their osteogenic derivatives (Andersen, D., et al., 2011).
      References
      Product Information
      FormatPurified
      Control
      • Daudi cell lysates
      PresentationPurified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect HLA-DRB1 using this Anti-HLA-DRB1 Antibody, clone DJ9 validated for use in Western Blotting, ICC, IHC, Flow Cytometry.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      • Flow Cytometry
      Application NotesThis antibody has been shown to work in Immunocytochemistry (Andersen, D., et al. (2011)). This antibody has been shown to work in Immunohistochemistry (Andersen, D., et al. (2011)). This antibody has been shown to work in Flow Cytometry (Andersen, D., et al. (2011)).
      Biological Information
      ImmunogenWhole hMSC-TERT Cells
      CloneDJ9
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody recognizes human HLA-DRB1.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • HLA-DRB1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~30 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in Daudi cell lysates. Western Blot Analysis: A 1:100,000 dilution of this antibody detected HLA-DRB1 in Duadi cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABD90 04053252698835

      Documentation

      Anti-HLA-DRB1 Antibody, clone DJ9 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-HLA-DRB1 Antibody, clone DJ9 Certificates of Analysis

      TitleLot Number
      Anti-HLA-DRB1, clone DJ9 2476792
      Anti-HLA-DRB1, clone DJ9 - 2536491 2536491
      Anti-HLA-DRB1, clone DJ9 - 3470767 3470767
      Anti-HLA-DRB1, clone DJ9 - 3609385 3609385
      Anti-HLA-DRB1, clone DJ9 - 3800850 3800850
      Anti-HLA-DRB1, clone DJ9 - 3888816 3888816
      Anti-HLA-DRB1, clone DJ9 - 4163449 4163449
      Anti-HLA-DRB1, clone DJ9 - 4204608 4204608
      Anti-HLA-DRB1, clone DJ9 - Q2060585 Q2060585
      Anti-HLA-DRB1, clone DJ9 -2550996 2550996

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies