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ABS1065 Anti-CES2 Antibody

This Anti-CES2 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of CES2 .

Anti-CES2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: CES2, ICE UniProt Number: O00748
ABS1065
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABS1065
      DescriptionAnti-CES2 Antibody
      Alternate Names
      • Cocaine esterase
      • CES2
      • Carboxylesterase 2
      • hCE-2
      • CE-2
      • Methylumbelliferyl-acetate deacetylase 2
      Background InformationCocaine esterase (EC 3.1.1.1; EC 3.1.1.56; EC 3.1.1.84; UniProt O00748; also known as Carboxylesterase 2, CE-2, hCE-2, iCE, Intestinal carboxylesterase, Liver carboxylesterase-2, Methylumbelliferyl-acetate deacetylase 2) is encoded by the CES2 (also known as CES2A1, ICE) gene (Gene ID 8824) in human. Human carboxylesterase 1 (CES1 or CES1A) and carboxylesterase 2 (CES2) are serine esterases responsible for the hydrolysis of ester and amide bonds present in several types of chemical compounds, including prodrugs such as imidapril and irinotecan (CPT-11). CES1A and CES2 are the two major members among human CES genes. CES1 is predominantly expressed in the liver and the lung, whereas CES2 is expressed in the gastrointestinal tract and the liver.
      References
      Product Information
      FormatSerum
      PresentationRabbit polyclonal antibody in serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-CES2 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of CES2 .
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected CES2 in rat liver and human liver tissue.
      Biological Information
      ImmunogenLinear peptide corresponding to the C-terminus of human CES2.
      EpitopeC-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityExpected to react with both spliced isoforms.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Non-Human Primate based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CES2
      • ICE
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~58 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse liver tissue lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected CES2 in 10 µg of mouse liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS1065 04055977298109