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MABE627 Anti-AURKB, clone 13E8D3 Antibody

MABE627
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABE627
      Replaces04-1036
      DescriptionAnti-AURKB, clone 13E8D3 Antibody
      Alternate Names
      • Aurora kinase B
      • AURKB
      Background InformationAurora A, B, and C, are members of the serine/threonine kinase family. These have been identified as important regulators of the mitotic cell division process. Aurora B, specifically, is involved in the regulation of centrosome function, bipolar spindle assembly, and chromosome segregation. Aurora-C is a chromosomal passenger protein that form complexes with Aurora B and INCENP (which binds and activates Aurora C in vivo and in vitro).
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-AURKB, clone 13E8D3 Antibody is an antibody against AURKB for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPurified recombinant fragment of AURKB expressed in E. Coli.
      Clone13E8D3
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • AURKB
      • AIK2
      • AIM1
      • AIRK2
      • ARK2
      • STK1
      • STK12
      • STK5
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~22 and ~43 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in truncated AURKB recombinant protein and SKN-SH cell lysate.

      Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected truncated AURKB recombinant protein and SKN-SH cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABE627 04055977172256