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09-279 Anti-20S proteasome subunit β6 Antibody

Detect 20S proteasome subunit β6 using this Anti-20S proteasome subunit β6 Antibody validated for use in WB, IH.

Anti-20S proteasome subunit β6 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Protein Trafficking Research Sub-Category: Ubiquitin & Ubiquitin Metabolism Gene Symbol: PSMB1, FLJ25321, HC5, KIAA1838, PSC5, PMSB1 UniProt Number: P20618
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09-279
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RbWB, IHCRbSerumPolyclonal Antibody
      Description
      Catalogue Number09-279
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-20S proteasome subunit β6 Antibody
      Alternate Names
      • C5
      References
      Product Information
      FormatSerum
      Presentation100 µL of purified antiserum in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
      Quality LevelMQ100
      Applications
      ApplicationDetect 20S proteasome subunit β6 using this Anti-20S proteasome subunit β6 Antibody validated for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Biological Information
      ImmunogenPeptide corresponding to residues 185-198 of human proteasome subunit β6 conjugated to KLH.
      HostRabbit
      SpecificityRecognizes proteasome subunit β6
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rabbit
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.
      Gene Symbol
      • PSMB1
      • FLJ25321
      • HC5
      • KIAA1838
      • PSC5
      • PMSB1
      Purification MethodSerum
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P20618 # The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
      SIZE: 241 amino acids; 26489 Da
      SUBUNIT: The proteasome is composed of at least 15 non identical subunits which form a highly ordered ring-shaped structure.
      SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
      SIMILARITY: SwissProt: P20618 ## Belongs to the peptidase T1B family.
      Molecular Weight26 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of shipment for up to 12 months.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      09-279 04053252474767