Wenn Sie das Fenster schließen, wird Ihre Konfiguration nicht gespeichert, es sei denn, Sie haben Ihren Artikel in die Bestellung aufgenommen oder zu Ihren Favoriten hinzugefügt.
Klicken Sie auf OK, um das MILLIPLEX® MAP-Tool zu schließen oder auf Abbrechen, um zu Ihrer Auswahl zurückzukehren.
Wählen Sie konfigurierbare Panels & Premixed-Kits - ODER - Kits für die zelluläre Signaltransduktion & MAPmates™
Konfigurieren Sie Ihre MILLIPLEX® MAP-Kits und lassen sich den Preis anzeigen.
Konfigurierbare Panels & Premixed-Kits
Unser breites Angebot enthält Multiplex-Panels, für die Sie die Analyten auswählen können, die am besten für Ihre Anwendung geeignet sind. Unter einem separaten Register können Sie das Premixed-Cytokin-Format oder ein Singleplex-Kit wählen.
Kits für die zelluläre Signaltransduktion & MAPmates™
Wählen Sie gebrauchsfertige Kits zur Erforschung gesamter Signalwege oder Prozesse. Oder konfigurieren Sie Ihre eigenen Kits mit Singleplex MAPmates™.
Die folgenden MAPmates™ sollten nicht zusammen analysiert werden: -MAPmates™, die einen unterschiedlichen Assaypuffer erfordern. -Phosphospezifische und MAPmate™ Gesamtkombinationen wie Gesamt-GSK3β und Gesamt-GSK3β (Ser 9). -PanTyr und locusspezifische MAPmates™, z.B. Phospho-EGF-Rezeptor und Phospho-STAT1 (Tyr701). -Mehr als 1 Phospho-MAPmate™ für ein einziges Target (Akt, STAT3). -GAPDH und β-Tubulin können nicht mit Kits oder MAPmates™, die panTyr enthalten, analysiert werden.
.
Bestellnummer
Bestellinformationen
St./Pkg.
Liste
Dieser Artikel wurde zu Ihren Favoriten hinzugefügt.
Wählen Sie bitte Spezies, Panelart, Kit oder Probenart
Um Ihr MILLIPLEX® MAP-Kit zu konfigurieren, wählen Sie zunächst eine Spezies, eine Panelart und/oder ein Kit.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
Catalogue Number
Ordering Description
Qty/Pack
List
Dieser Artikel wurde zu Ihren Favoriten hinzugefügt.
Spezies
Panelart
Gewähltes Kit
Menge
Bestellnummer
Bestellinformationen
St./Pkg.
Listenpreis
96-Well Plate
Menge
Bestellnummer
Bestellinformationen
St./Pkg.
Listenpreis
Weitere Reagenzien hinzufügen (MAPmates erfordern die Verwendung eines Puffer- und Detektionskits)
Menge
Bestellnummer
Bestellinformationen
St./Pkg.
Listenpreis
48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Platzsparende Option Kunden, die mehrere Kits kaufen, können ihre Multiplex-Assaykomponenten in Kunststoffbeuteln anstelle von Packungen erhalten, um eine kompaktere Lagerung zu ermöglichen.
Dieser Artikel wurde zu Ihren Favoriten hinzugefügt.
Das Produkt wurde in Ihre Bestellung aufgenommen
Sie können nun ein weiteres Kit konfigurieren, ein Premixed-Kit wählen, zur Kasse gehen oder das Bestell-Tool schließen.
SCC253
Sigma-AldrichWB-F344 Rat Liver Progenitor Cell Line
The WB-F344 cell line is a well-established and versatile model for studies of liver cell renewal, differentiation, and origination of hepatic cancers.
More>>The WB-F344 cell line is a well-established and versatile model for studies of liver cell renewal, differentiation, and origination of hepatic cancers. Less<<
"Among adult organs, the liver has the unique ability to regenerate after injury, a feature that has generated a high level of interest in liver progenitor cells for therapeutic uses. Liver progenitor cells (also known as oval cells) have potential to differentiate into either of the two epithelial cell types in the liver, biliary epithelial cells or hepatocytes.1 The inherent versatility and clinical applicability of liver progenitor cells highlight the importance of cellular models for this cell type. WB-F344 is a highly cited, spontaneously immortalized rat liver progenitor cell line. WB-F344 cells are derived from adult tissue yet have the characteristic phenotype of oval cells and proliferate rapidly.3 WB-F344 cells express markers of liver progenitor cells, including EpCAM, Thy1, and α-fetoprotein.3 WB-F344 cells are non-tumorigenic, but can undergo neoplastic transformation both in response to treatment with carcinogenic agents4 and spontaneously when maintained in a post-confluent state.5 The WB-F344 cell line is a well-established and versatile model for studies of liver cell renewal, differentiation, and origination of hepatic cancers.
Source WB-F344 rat liver progenitor cell line was isolated from the liver epithelium of an adult Fischer-344 rat.2
References 1. Int J Exp Pathol 2005, 86(1): 1-18. 2. Stem Cells Cloning 2010, 3: 39-47. 3. Exp Cell Res 1984, 154(1): 38-52. 4. Am J Pathol 1989, 135(1): 63-71. 5. Am J Pathol 1998, 153(6): 1913-1921.
Background Information
Among adult organs, the liver has the unique ability to regenerate after injury, a feature that has generated a high level of interest in liver progenitor cells for therapeutic uses. Liver progenitor cells (also known as oval cells) have potential to differentiate into either of the two epithelial cell types in the liver, biliary epithelial cells or hepatocytes.1 The inherent versatility and clinical applicability of liver progenitor cells highlight the importance of cellular models for this cell type. WB-F344 is a highly cited, spontaneously immortalized rat liver progenitor cell line. WB-F344 cells are derived from adult tissue yet have the characteristic phenotype of oval cells and proliferate rapidly.3 WB-F344 cells express markers of liver progenitor cells, including EpCAM, Thy1, and α-fetoprotein.3 WB-F344 cells are non-tumorigenic, but can undergo neoplastic transformation both in response to treatment with carcinogenic agents4 and spontaneously when maintained in a post-confluent state.5 The WB-F344 cell line is a well-established and versatile model for studies of liver cell renewal, differentiation, and origination of hepatic cancers.
Source WB-F344 rat liver progenitor cell line was isolated from the liver epithelium of an adult Fischer-344 rat.2
References 1. Int J Exp Pathol 2005, 86(1): 1-18. 2. Stem Cells Cloning 2010, 3: 39-47. 3. Exp Cell Res 1984, 154(1): 38-52. 4. Am J Pathol 1989, 135(1): 63-71. 5. Am J Pathol 1998, 153(6): 1913-1921.
The WB-F344 cell line is a well-established and versatile model for studies of liver cell renewal, differentiation, and origination of hepatic cancers.
Key Applications
Cell Culture
Application Notes
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@emdmillipore.com.
Biological Information
Cell Line Type
Hepatocyte Cells
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance
• Each vial contains ≥ 1X106 viable cells. • Cells are tested negative for infectious diseases by a Mouse/Rat Comprehensive CLEAR Panel by Charles River Animal Diagnostic Services. • Cells are verified to be of rat origin and negative for inter-species contamination from mouse, human, chinese hamster, Golden Syrian hamster, and Non-human Primate (NHP) as assessed by a Contamination Clear panel by Charles River Animal Diagnostic Services • Cells are negative for mycoplasma contamination.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
The cells should be stored in liquid nitrogen until use. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting functionality.
