573102 Sigma-AldrichSTAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem
STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription.
More>> STAT3 Inhibitor VI, S3I-201, CAS 501919-59-1, is a cell-permeable compound that binds Stat3-SH2 domain and blocks Stat3 phosphorylation, dimerization, DNA-binding, & Stat3-dependent transcription. Less<<SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859
Empfohlene Produkte
Übersicht
| Replacement Information |
|---|
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 501919-59-1 | C₁₆H₁₅NO₇S |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 573102-10MG |
|
Kst.-Ampulle | 10 mg |
|
— | |
| 573102-25MG |
|
Kst.-Ampulle | 25 mg |
|
— |
| Description | |
|---|---|
| Overview | A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). Also available as a 50 mM solution in DMSO (Cat. No. 573130). |
| Catalogue Number | 573102 |
| Brand Family | Calbiochem® |
| Synonyms | 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859 |
| References | |
|---|---|
| References | Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
| Product Information | |
|---|---|
| CAS number | 501919-59-1 |
| Form | Light beige solid |
| Hill Formula | C₁₆H₁₅NO₇S |
| Chemical formula | C₁₆H₁₅NO₇S |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Purity | ≥95% by HPLC |
| Physicochemical Information |
|---|
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Bestellnummer | GTIN |
| 573102-10MG | 04055977266429 |
| 573102-25MG | 04055977266436 |
Documentation
STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem SDB
| Titel |
|---|
STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
|---|---|
| 573102 |
Literatur
| Übersicht |
|---|
| Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
Technische Informationen
| Titel |
|---|
| JAK/STAT Signaling Research Focus |