573096 Sigma-AldrichSTAT3 Inhibitor Peptide, Cell-Permeable
STAT3 Inhibitor Peptide, Cell-Permeable, is an analog of Stat3-SH2 domain-binding phosphopeptide with a C-terminal membrane translocating sequence. A selective, potent blocker of Stat3 activation.
More>> STAT3 Inhibitor Peptide, Cell-Permeable, is an analog of Stat3-SH2 domain-binding phosphopeptide with a C-terminal membrane translocating sequence. A selective, potent blocker of Stat3 activation. Less<<STAT3 Inhibitor Peptide, Cell-Permeable: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: PpYLKTK-mts, STAT3 Inhibitor IV
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Übersicht
| Replacement Information |
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Key Spec Table
| Empirical Formula |
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| C₉₂H₁₅₇N₂₀O₂₄P |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 573096-1MG |
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Kst.-Ampulle | 1 mg |
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| 573096-5MG |
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Kst.-Ampulle | 5 mg |
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| Description | |
|---|---|
| Overview | A cell-permeable analog of the Stat3-SH2 domain-binding phosphopeptide (Cat. No. 573095) that contains a C-terminal mts (membrane translocating sequence) and acts as a highly selective, potent blocker of Stat3 activation. Also suppresses constitutive Stat-3 dependent Src transformation with no effect on Stat-3 independent Ras transformation. The unphosphorylated inactive control peptide is also available under Cat. No. 573105. |
| Supplied as a trifluoroacetate salt. | |
| Catalogue Number | 573096 |
| Brand Family | Calbiochem® |
| Synonyms | PpYLKTK-mts, STAT3 Inhibitor IV |
| References | |
|---|---|
| References | Turkson, J., et al. 2001. J. Biol. Chem. 276, 45443. Rojas, M., et al. 1998. Nat. Biotechnol. 16, 370. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | White lyophilized solid |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₉₂H₁₅₇N₂₀O₂₄P |
| Chemical formula | C₉₂H₁₅₇N₂₀O₂₄P |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | Blocker of Stat3 activation |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | H-Pro-Tyr-(PO₃H₂)-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-OH |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Bestellnummer | GTIN |
| 573096-1MG | 07790788051730 |
| 573096-5MG | 07790788051747 |
Documentation
STAT3 Inhibitor Peptide, Cell-Permeable SDB
| Titel |
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STAT3 Inhibitor Peptide, Cell-Permeable Analysenzertifikate
| Titel | Chargennummer |
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| 573096 |
Literatur
| Übersicht |
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| Turkson, J., et al. 2001. J. Biol. Chem. 276, 45443. Rojas, M., et al. 1998. Nat. Biotechnol. 16, 370. |
Broschüre
| Titel |
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| An Introduction to Inhibitors and Their Biological Applications - 1st Edition |
Technische Informationen
| Titel |
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| JAK/STAT Signaling Research Focus |
Literaturstellen
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