480066 Sigma-AldrichNecrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem
Necrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties.
More>> Necrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties. Less<<Synonyme: 5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i
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Übersicht
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Key Spec Table
CAS # | Empirical Formula |
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64419-92-7 | C₁₂H₁₁N₃OS |
Preis & Verfügbarkeit
Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
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480066-5MG |
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Kst.-Ampulle | 5 mg |
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Description | |
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Overview | A cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) that is devoid of anti-necroptotic properties and serves as a suitable inactive control. Note: This inactive inhibitor of necrosis should not be used in high concentration. |
Catalogue Number | 480066 |
Brand Family | Calbiochem® |
Synonyms | 5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i |
References | |
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References | Takahashi et al. 2012. Cell Death and Disease 3, e437. Degterev, A., et al. 2005. Nat. Chem. Biol. 1, 112. |
Product Information | |
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CAS number | 64419-92-7 |
ATP Competitive | N |
Form | Light yellow crystalline solid |
Hill Formula | C₁₂H₁₁N₃OS |
Chemical formula | C₁₂H₁₁N₃OS |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications | |
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Application | Necrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties. |
Biological Information | |
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Primary Target | Inactive control for Nec-1 (Cat. No. 480065) |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
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Packaged under inert gas | Packaged under inert gas |
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Specifications |
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Global Trade Item Number | |
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Bestellnummer | GTIN |
480066-5MG | 04055977201888 |
Documentation
Necrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem SDB
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Necrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem Analysenzertifikate
Titel | Chargennummer |
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480066 |
Literatur
Übersicht |
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Takahashi et al. 2012. Cell Death and Disease 3, e437. Degterev, A., et al. 2005. Nat. Chem. Biol. 1, 112. |