235427 Sigma-AldrichInSolution™ Caspase-3 Inhibitor I, Cell-Permeable - Calbiochem
The InSolution™ Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
More>> The InSolution™ Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications. Less<<SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: Cell-permeable, DEVD-CHO; CPP32/Apopain Inhibitor, Cell-permeable
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Übersicht
| Replacement Information |
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Key Spec Table
| Empirical Formula |
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| C₉₄H₁₅₈N₂₀O₂₇ |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 235427-1MG |
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Glasflasche | 1 mg |
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| Description | |
|---|---|
| Catalogue Number | 235427 |
| Brand Family | Calbiochem® |
| Synonyms | Cell-permeable, DEVD-CHO; CPP32/Apopain Inhibitor, Cell-permeable |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Liquid |
| Formulation | A 5 mM (1 mg/100 µl) solution of Caspase-3 Inhibitor I, Cell-permeable (Cat. No. 235423) in DMSO. |
| Hill Formula | C₉₄H₁₅₈N₂₀O₂₇ |
| Chemical formula | C₉₄H₁₅₈N₂₀O₂₇ |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | caspase-3 |
| Primary Target IC<sub>50</sub> | 200 pM inhibiting PARP cleavage in cultured human osteosarcoma cell extracts |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Peptide Sequence | Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information | |
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| R Phrase | R: 36/38 Irritating to eyes and skin. |
| S Phrase | S: 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Bestellnummer | GTIN |
| 235427-1MG | 04055977217056 |
Documentation
InSolution™ Caspase-3 Inhibitor I, Cell-Permeable - Calbiochem SDB
| Titel |
|---|
InSolution™ Caspase-3 Inhibitor I, Cell-Permeable - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
|---|---|
| 235427 |
Literatur
| Übersicht |
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| Lin, Y.-Z., et al. 1996. J. Biol. Chem. 271, 5305. Nicholson, D.W. 1996. Nature Biotechnol. 14, 297. Schlegel, J., et al. 1996. J. Biol. Chem. 271, 1841. Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255. Nicholson, D.W., et al. 1995. Nature 376, 37. Tewari, M., et al. 1995. Cell 81, 801. Lazebnik, Y.A., et al. 1994. Nature 371, 346. |
Broschüre
| Titel |
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| Caspases and other Apoptosis Related Tools Brochure |
Literaturstellen
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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