401478 Sigma-AldrichIκB Kinase Inactive Control Peptide, Cell-Permeable - Calbiochem
An inactive control for IκB Kinase Inhibitor Peptide.
More>> An inactive control for IκB Kinase Inhibitor Peptide. Less<<SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: Ac-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂
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Übersicht
Key Spec Table
| Empirical Formula |
|---|
| C₁₃₈H₂₂₉N₃₇O₄₃S |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 401478-1MG |
|
Kst.-Ampulle | 1 mg |
|
— |
| Description | |
|---|---|
| Overview | An inactive control for IκB Kinase Inhibitor Peptide (Cat. No. 401477). A 14-amino acid peptide corresponding to the mutated recognition sequence of IκB (Ser32→Ala and Ser36→Ala) fused to the hydrophobic region of the fibroblast growth factor signal peptide to aid in cellular delivery. Does not have any inhibitory effect on LPS-induced IκB degradation by IκB kinases (IKK) in RAW 264.7 cells at 50 µg/ml. |
| Catalogue Number | 401478 |
| Brand Family | Calbiochem® |
| Synonyms | Ac-AAVALLPAVLLALLAPDDRHDAGLDAMKDE-NH₂ |
| References | |
|---|---|
| References | Swaroop, N., et al. 2001. Pharm. Res. 18, 1631. Traenckner, E.B., et al. 1995. EMBO J. 14, 2876. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Off-white to white solid |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₁₃₈H₂₂₉N₃₇O₄₃S |
| Chemical formula | C₁₃₈H₂₂₉N₃₇O₄₃S |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | An inactive control for IκB Kinase Inhibitor Peptide |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Peptide Sequence | Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Asp-Arg-His-Asp-Ala-Gly-Leu-Asp-Ala-Met-Lys-Asp-Glu-NH₂ |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Bestellnummer | GTIN |
| 401478-1MG | 04055977211931 |