370677 Sigma-AldrichGuanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem
A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II.
More>> A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Less<<SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: Rp-8-pCPT-cGMPS, TEA, PKG Inhibitor III
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Übersicht
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Key Spec Table
| Empirical Formula |
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| C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
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| 370677-1UMOL |
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Kst.-Ampulle | 1 umol |
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| Description | |
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| Overview | A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Significantly more lipophilic and membrane-permeable than Rp-cGMPS or Rp-8-Br-cGMPS (Cat. No. 370674). Note: 1 µmol = 0.61 mg. |
| Catalogue Number | 370677 |
| Brand Family | Calbiochem® |
| Synonyms | Rp-8-pCPT-cGMPS, TEA, PKG Inhibitor III |
| Product Information | |
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| ATP Competitive | N |
| Declaration | Sold under license of U.S. Patent 5,625,056, Patents DE 3,802,865.4, and DE 4,217,679 issued to BIOLOG LSI. |
| Form | Lyophilized |
| Hill Formula | C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
| Chemical formula | C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | PKG1α |
| Purity | ≥99% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Specifications |
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| Global Trade Item Number | |
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| Bestellnummer | GTIN |
| 370677-1UMOL | 04055977191707 |
Documentation
Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem SDB
| Titel |
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Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
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| 370677 |
Literatur
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| Abd Alla, S., et al. 1996. Eur. J. Biochem. 241, 498. Lee, S.J., et al. 1996. Dev. Biol. 180, 324. Van Uffelen, B.E., et al. 1996. J. Leukoc. Biol. 60, 94. Willmott, N., et al. 1996. J. Biol. Chem. 271, 3699. Butt, E., et al. 1994. Eur. J. Pharmacol. 269, 265. |