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14-568M Fgr Protein, active, 250 µg

Active, N-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end, for use in Kinase Assays.

Fgr Protein, active, 250 µg: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
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14-568M
250 µg  Also available in 10 μg size (cat#14-568) and in bulk (cat# 14-568-K).
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      Übersicht

      Replacement Information
      Description
      Catalogue Number14-568M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionFgr Protein, active, 250 µg
      OverviewN-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
      Gene Symbol
      • FGR
      • P55-FGR
      • p58c-fgr
      • MGC75096
      • c-src2
      • p55c-fgr
      • SRC2
      • c-fgr
      • FLJ43153
      Protein TargetFgr
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummarySIZE: 529 amino acids; 59479 Da
      SUBUNIT: Binds PTPNS1 (By similarity).
      SIMILARITY: SwissProt: P09769 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
      Molecular Weight60.4kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-568) and in bulk (cat# 14-568-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      14-568M 04053252369582

      Verwandte Produkte & Anwendungen

      Alternative Packsize

      Bestellnummer Beschreibung  
      14-568 Fgr Protein, active, 10 µg Preis & Verfügbarkeit

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      Kategorien

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases