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204883 Complement C1-Esterase Inhibitor, Human

Complement C1-Esterase Inhibitor, Human, is a native, single-chain glycoprotein that is involved in regulation of complement, coagulation, fibrinolytic and contact systems of circulating plasma.

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204883
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204883-1MG
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      		 Kst.-Ampulle 1 mg
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      Description
      OverviewNative, human C1-esterase. Single-chain glycoprotein present in normal human serum at 180 µg/ml. Involved in regulation of complement, coagulation, fibrinolytic and contact (kinin-forming) systems of circulating blood plasma. The only known inhibitor of activated C1r and C1s complement enzymes. The presence of either hereditary or acquired deficiencies of C1 inhibitor produce susceptibility to recurrent attacks of angioedema.
      Catalogue Number204883
      Brand Family Calbiochem®
      References
      ReferencesBowen, B., et al. 2001. Clin. Immunol. 98, 157.
      Davis, A.E. 1988. Ann. Rev. Immunol. 6, 595.
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.3, sterile-filtered through a 0.22 µm filter.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Biological activity≥80% of C1-esterase inhibitor will bind activated C1s.
      Purity≥90% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      ContaminantsIgG, IgA, IgM, albumin, C3, C4, or ceruloplasmin: ≤trace amounts
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Bestellnummer GTIN
      204883-1MG 04055977219777