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ABN415 Anti-TRAPPC1 Antibody

This Anti-TRAPPC1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of TRAPPC1.

Anti-TRAPPC1 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Neuroscience, Neuroscience Research Sub-Category: Ion Channels & Transporters, Neurotransmitters & Receptors Gene Symbol: BET5, MUM2 UniProt Number: Q9Y5R8
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ABN415
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN415
      DescriptionAnti-TRAPPC1 Antibody
      Alternate Names
      • TRAPPC-1
      • Trafficking protein particle complex subunit 1
      • BET5 homolog
      • Multiple myeloma protein 2
      • MUM-2
      • MUM2
      Background InformationTRAPPC1 is one part of a larger protein complex called the TRAPP (transport protein particle) complex vital to Golgi function and transport. TRAPPC1 is localized to the Golgi and endoplasmic reticulum. Vesicle-mediated transport is a process carried out by virtually all cells and is required for the proper targeting and secretion of proteins. As such, there are numerous proteins involved to ensure that the proteins are properly transported, targeted, tethered, and localized. The TRAPP complex is just one such complex but it is one of the most studied. Mutations in TRAPPC proteins can lead to serious disorders including muscular dystrophy and myopathy such as that seen with mutations associated with TRAPPC11 (a related gene to TRAPPC1).
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-TRAPPC1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of TRAPPC1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 0.25 µg/mL from a representative lot detected TRAPPC1 in 5 µg of mouse brain tissue lysate.
      Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TRAPPC1 in human cerebral cortex, cerebellum, and kidney.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the Near C-terminus of Human TRAPPC1.
      EpitopeNear C-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Monkey based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • BET5
      • MUM2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~19 kDa observed. The endogenous band appears at ~31kDa (mouse brain) while the transfected band appears at ~19kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in TRAPPC1 transfected HEK293T cell lysate.

      Western Blotting Analysis: 0.25 µg/mL of this antibody detected TRAPPC1 in 5 µg of TRAPPC1 transfected HEK293T cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABN415 04055977052909