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AB10202 Anti-MEOX1 Antibody

Anti-MEOX1 Antibody is an antibody against MEOX1 for use in WB.

Anti-MEOX1 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Stem Cell Research Research Sub-Category: Mesenchymal Stem Cells Gene Symbol: MOX1 UniProt Number: P50221
AB10202
100 µl  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, H, R, BWBRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB10202
      DescriptionAnti-MEOX1 Antibody
      Alternate Names
      • mesenchyme homeo box 1
      • mesenchyme homeobox 1
      Background InformationMEOX1 (Mesenchyme homobox 1) is a transcription factor that is expressed in the developing mesoderm, and plays a role in the commitment of stem cells to the skeletal muscle lineage. This gene, which encodes a member of a subfamily of non-clustered, diverged homeobox-containing genes, is up-regulated by overexpression of GLI2 and functions upstream of the PAX genes—preferentially interacting with PAX1, over PAX3. More recently, MEOX1 has also been shown to play a role in regulating the proliferation and differentiation pathways of embryonic stem cells through its role as a gate keeper to mesoderm induction and its earliest regional specification, somitogenesis, and myogenic/sclerotomal differentiation.
      References
      Product Information
      FormatPurified
      PresentationPurified Rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.
      Applications
      ApplicationAnti-MEOX1 Antibody is an antibody against MEOX1 for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting: Recommended working dilutions are 1:100 – 1:200.
      Biological Information
      ImmunogenSynthetic MEOX1 peptide, aa. 238-254.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from human MEOX1 protein.
      Species Reactivity
      • Mouse
      • Human
      • Rat
      • Bovine
      Species Reactivity NoteReacts with mouse. Comparison of sequence homology suggests that this antibody will also react in human, rat, and bovine; however, reactivity with other species has not been tested.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
      Gene Symbol
      • MOX1
      UniProt Number
      UniProt SummaryFUNCTION: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation (By similarity).
      SUBCELLULAR LOCATION: Nucleus (Potential).
      SIMILARITY: Contains 1 homeobox DNA-binding domain.
      Stem Cell Type
      • Mesenchymal Stem Cells
      Molecular Weight28 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by western blot on mouse kidney cytosol lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8°C in undiluated aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.
      Packaging Information
      Material Size100 µl
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      AB10202 04053252621895