Millipore Sigma Vibrant Logo

AB2233 Anti-Galanin Antibody

View Products on Sigmaaldrich.com
AB2233
100 µL   
Preis wird abgerufen...
Preis nicht abrufbar
Die Mindestmenge muss ein Vielfaches sein von
Maximum Quantity is
Bei Bestätigung Weitere Informationen
Sie haben () gespart
 
Bitte erfragen
Eingeschränkte Verfügbarkeit
Eingeschränkte Verfügbarkeit
Lieferbar 
Produkt wurde eingestellt
Begrenzter Lagerbestand
Bestätigung der Verfügbarkeit erforderlich
    Restmenge: Angebot folgt
      Restmenge: Angebot folgt
      Bitte erfragen
      Kontakt zum Kundenservice
      Contact Customer Service

      Sonderaktionen

       

      Kontakt zum Kundenservice

      Übersicht

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RIH(P)RbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB2233
      DescriptionAnti-Galanin Antibody
      Alternate Names
      • galanin prepropeptide
      • galanin-message-associated peptide
      • galanin-related peptide
      Background InformationGalanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer's disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.
      References
      Product Information
      FormatSerum
      Control
      • Rat Cerebellum Tissue
      PresentationSerum with 0.05% NaN3
      Quality LevelMQ100
      Applications
      ApplicationDetect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Biological Information
      ImmunogenSynthetic Linear Peptide
      HostRabbit
      SpecificityCat. # AB2233 recognizes Galanin
      Species Reactivity
      • Rat
      Species Reactivity NoteRat. May react with mouse, human and Sus Scrofa based on sequence homology. Reactivity with other species has not been determined.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GAL1
      • GALN
      • GLNN
      • GMAP
      • MGC40167
      • galanin
      UniProt Number
      UniProt SummaryFUNCTION: Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.
      LOCATION: Secreted.
      SIMILARITY: Belongs to the galanin family.
      Molecular Weight13.3 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by Immunhistochemistry on rat cerebellum tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C for up to 1 year from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      AB2233 04053252321740

      Documentation

      Anti-Galanin Antibody SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Anti-Galanin Antibody Analysenzertifikate

      TitelChargennummer
      Anti-Galanin - 2433379 2433379
      Anti-Galanin - 1978014 1978014
      Anti-Galanin - 2273991 2273991
      Anti-Galanin - 3254574 3254574
      Anti-Galanin - 3740962 3740962
      Anti-Galanin - 3862682 3862682
      Anti-Galanin - 3886616 3886616
      Anti-Galanin - 4104659 4104659
      Anti-Galanin - JBC1793809 JBC1793809
      Anti-Galanin - NG1551492 NG1551492

      Literatur

      ÜbersichtAnwendungSpeziesPub Med ID
      Prolonged acetylsalicylic-acid-supplementation-induced gastritis affects the chemical coding of the stomach innervating vagal efferent neurons in the porcine dorsal motor vagal nucleus (DMX).
      Gańko, M; Całka, J
      Journal of molecular neuroscience : MN  54  188-98  2014

      Abstract anzeigen
      ImmunohistochemistryPorcine24643520 24643520

      Verwandte Produkte & Anwendungen

      Related Products

      Bestellnummer Beschreibung  
      AB5909 Anti-Galanin Antibody Preis & Verfügbarkeit

      Kategorien

      Life Science Research > Antibodies and Assays > Primary Antibodies