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ABN342 Anti-FEZ2 Antibody

Detect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.

Anti-FEZ2 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Neuroscience, Neuroscience Research Sub-Category: Developmental Neuroscience, Neuroregenerative Medicine Gene Symbol: FEZ2 UniProt Number: Q9UHY8
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ABN342
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWB, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN342
      DescriptionAnti-FEZ2 Antibody
      Alternate Names
      • Fasciculation and elongation protein zeta-2
      • Zygin II
      • Zygin-2
      Background InformationFasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
      References
      Product Information
      FormatAffinity Purified
      Control
      • 3T3 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.
      Key Applications
      • Western Blotting
      • Immunofluorescence
      Application NotesImmunofluorescence Analysis: 5 µg/mLfrom a representative lot detected FEZ2 in human brain tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human FEZ2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Mouse
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • FEZ2
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~38/50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in 3T3 cell lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected FEZ2 in 15 µg of 3T3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      ABN342 04053252847431

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      Kategorien

      Life Science Research > Antibodies and Assays > Primary Antibodies