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MABC127 Anti-Ephrin-B2 Antibody

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MABC127
100 µg  
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      Übersicht

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC127
      DescriptionAnti-Ephrin-B2 Antibody
      Alternate Names
      • Ephrin-B2
      • EPH-related receptor tyrosine kinase ligand 5
      • LERK-5
      • HTK ligand
      • HTK-L
      Background InformationEphrin-B2 is also called EPH-related receptor tyrosine kinase ligand 5 (LERK-5) and HTK ligand (HTK-L). Ephrin-B2 is a cell surface transmembrane ligand for the Eph tyrosine kinase family of receptors. Ephrin-B2 binds Eph receptors on adjacent cells, leading to contact-dependent bidirectional signaling, which is critical for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-B2 is expressed in lung and kidney and together with EPHB4 is involved in heart morphogenesis and angiogenesis.
      References
      Product Information
      FormatPurified
      Control
      • Mouse lung tissue lysate
      PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Ephrin-B2, clone 10H1.1, Cat. No. MABC127, is a mouse monoclonal antibody that detcets Ephrin-B2 and has been tested for use in immunohitochemistry and Western Blotting.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected Ephrin-B2 in rat and human lung tissue lysate.

      Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Ephrin-B2 in IHC.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Ephrin-B2.
      Clone10H1.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgMκ
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • EFNB2
      • EPLG5
      • HTKL
      • LERK5
      UniProt Number
      Molecular Weight~65 kDa observed. The calculated molecular weight of this protein is ~37 kDa; however, this protein has been observed at 65-70 kDa (Attwood, B. K., et al. (2011). Nature. 473(7347):372–375.; Lin, K. T., et al. (2008). J Biol Chem. 283(43):28969-28979.).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse lung tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Ephrin-B2 in 10 µg of mouse lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      MABC127 04053252859984

      Documentation

      Anti-Ephrin-B2 Antibody SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Anti-Ephrin-B2 Antibody Analysenzertifikate

      TitelChargennummer
      Anti-Ephrin-B2, Clone 10H1.1 - 4103691 4103691
      Anti-Ephrin-B2, clone 10H1.1 - Q2145000 Q2145000
      Anti-Ephrin-B2, clone 10H1.1 - 3378624 3378624
      Anti-Ephrin-B2, clone 10H1.1 - 3729952 3729952
      Anti-Ephrin-B2, clone 10H1.1 -2523884 2523884
      Anti-Ephrin-B2, clone 10H1.1 -2596511 2596511
      Anti-Ephrin-B2, clone 10H1.1 -2619690 2619690
      Anti-Ephrin-B2, clone 10H1.1 -2668536 2668536
      Anti-Ephrin-B2, clone 10H1.1 -2676711 2676711
      Anti-Ephrin-B2, clone 10H1.1 -2756666 2756666