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681640 Wee1 Inhibitor - CAS 622855-37-2 - Calbiochem

681640
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Tabulka spec. kláve

CAS #Empirical Formula
622855-37-2C₂₀H₁₁ClN₂O₃

Products

Katalogové čísloBalení ks/bal.
681640-1MG Plastová ampulka 1 mg
Description
OverviewA pyrrolocarbazole compound that acts as a potent, ATP-binding site-targeting inhibitor of Wee1 (IC50 = 11 nM) in an ATP-competitive manner and displays ~40-fold selectivity over the related checkpoint kinase Chk1 (IC50 = 440 nM).
Catalogue Number681640
Brand Family Calbiochem®
Synonyms4-(2-Chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3-(2H,6H)-dione, Chk1 Inhibitor V
References
ReferencesPalmer, B.D., et al. 2006. J. Med. Chem. 49, 4896.
Product Information
CAS number622855-37-2
ATP CompetitiveY
FormLight orange solid
Hill FormulaC₂₀H₁₁ClN₂O₃
Chemical formulaC₂₀H₁₁ClN₂O₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetWee1
Primary Target IC<sub>50</sub>11 nM
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Katalogové číslo GTIN
681640-1MG 04055977260182