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662094 Ubiquitin Conjugating Enzyme 6, His•Tag®, Human, Recombinant, E. coli

662094
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information
Description
Overview

This product has been discontinued.





Recombinant, human ubiquitin conjugating enzyme 6 fused to a His•Tag® sequence and expressed in E. coli. E2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. A closely related member of the UbcH5 family, UbcH6 has been implicated in ER degradation of aberrant proteins. UbcH6 utilizes Nedd4 as its ubiquitin-protein ligase.
Catalogue Number662094
Brand Family Calbiochem®
Synonyms(His)₆ UbcH6 (E2)
References
ReferencesAnan, T., et al. 1998. Genes Cells 3, 751.
Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
Seufert, W., et al. 1990. EMBO J. 9, 4535.
Product Information
FormLiquid
FormulationIn 200 mM NaCl, 50 mM Hepes, 0.1 mM DTT, 10% glycerol, pH 8.0.
Applications
Biological Information
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
662094 0

Documentation

Ubiquitin Conjugating Enzyme 6, His•Tag®, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
662094

References

Přehled odkazů
Anan, T., et al. 1998. Genes Cells 3, 751.
Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
Seufert, W., et al. 1990. EMBO J. 9, 4535.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-September-2008 RFH
Synonyms(His)₆ UbcH6 (E2)
DescriptionRecombinant, human ubiquitin conjugating enzyme 6 fused to a His•Tag® sequence and expressed in E. coli. E2 ubiquitin-conjugating enzymes are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-Lysine of proteins designated for degradation. A closely related member of the UbcH5 family, UbcH6 has been implicated in ER degradation of aberrant proteins. UbcH6 utilizes Nedd4 as its ubiquitin-protein ligase.
FormLiquid
FormulationIn 200 mM NaCl, 50 mM Hepes, 0.1 mM DTT, 10% glycerol, pH 8.0.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesAnan, T., et al. 1998. Genes Cells 3, 751.
Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
Seufert, W., et al. 1990. EMBO J. 9, 4535.