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662098 UbcH5c Conjugating Enzyme E2, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: UBD2D3, Ubiquitin-conjugating enzyme E2 D3

662098
  
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Description
OverviewFull-length, recombinant, human UbcH5c expressed in E. coli. UbcH5c, an E2 ubiquitin ligase, is highly homologous to the yeast UbC4/5 family of E2 enzymes. UbcH5c, together with UbcH5a and UbcH5b, are the most active class of E2 enzymes in cell extracts and are associated with regulation of transcription factors such as p53, NF-κB3, and c-Fos. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
Catalogue Number662098
Brand Family Calbiochem®
SynonymsUBD2D3, Ubiquitin-conjugating enzyme E2 D3
References
ReferencesBrzovic, P.S., et al. 2006. Cell Cycle 5, 2867.
Gehrke, S.G., et al. 2003 Blood. 101, 3288.
Nuber, U., And Scheffner, M., 1999. J. Biol. Chem. 274, 7576.
Schwarz, S.E., et al. 1998. J. Biol. Chem. 273, 12148.
Jensen, J., et al. 1995. J. Biol. Chem. 270, 30408.
Scheffner, M., et al. 1994. Proc. Natl. Acad. Sci. 91, 8797.
Product Information
FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.0.
Quality LevelMQ100
Biological Information
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Katalogové číslo GTIN
662098 0