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537011 Prolyl Endopeptidase Inhibitor II - CAS 108708-25-4 - Calbiochem

537011
  
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Tabulka spec. kláve

CAS #Empirical Formula
108708-25-4C₁₈H₂₂N₂O₄
Description
OverviewA cell-permeable dipeptide aldehyde that acts as a specific, potent, slow, and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki = 350 pM and 500 pM for mouse brain and human brain, respectively). Reported to form a hemiacetal with the active site serine of the enzyme.
Catalogue Number537011
Brand Family Calbiochem®
SynonymsZ-PP-CHO
References
ReferencesFülöp, V., et al. 1998. Cell 94, 161.
Kahyaoglu, A., et al. 1997. Biochem. J. 322, 839.
Bakker, A.V., et al. 1990. Biochem. J. 271, 559.
Wilk, S., and Orlowski, M. 1983. J. Neurochem. 41, 69.
Product Information
CAS number108708-25-4
ATP CompetitiveN
FormColorless to off-white oil
Hill FormulaC₁₈H₂₂N₂O₄
Chemical formulaC₁₈H₂₂N₂O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetMouse brain prolylendooeotidase
Primary Target K<sub>i</sub>350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Pro-Pro-CHO
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Katalogové číslo GTIN
537011 0