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537009 Progranulin, CF, Mouse, Recombinant

Progranulin, CF, Mouse, Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PC cell-derived growth factor (PCDGF)

537009
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

Purity
≥90% by SDS-PAGE
Description
Overview

This product has been discontinued.



Recombinant, mouse progranulin, consisting of amino acids 18-589, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. Progranulin is an ubiquitously expressed, secreted glycoprotein that is involved in regulation of cell proliferation.
Catalogue Number537009
Brand Family Calbiochem®
SynonymsPC cell-derived growth factor (PCDGF)
References
ReferencesLiu, Y. et al. 2007. BMC Cancer 7, 22.
Xu, K. et al. 2007. J. Biol. Chem. 282, 11347.
Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727.
Davidson, B. et al. 2004. Cancer 100, 2139.
Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510.
Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113.
He, Z. et al. 2003. Nat. Med. 9, 225.
He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600.
Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136.
Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221.
Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31.
Zhu, J. et al. 2002. Cell 111, 867.
Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993.
Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165.
Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331.
Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202.
Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863.
Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073.
Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.
Product Information
FormLyophilized
FormulationLyophilized from 0.2 µm filtered PBS.
Quality LevelMQ100
Applications
Biological Information
Biological activitySignificantly enhances neurite outgrowth of E18 rat embryonic cortical neurons using 4-16 µg/ml progranulin immobilized on nitrocelluose-coated microplates.
Purity≥90% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: ≤1.0 EU/µg protein
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
537009 0

Documentation

Progranulin, CF, Mouse, Recombinant MSDS

Title

Safety Data Sheet (SDS) 

Progranulin, CF, Mouse, Recombinant Certificates of Analysis

TitleLot Number
537009

References

Přehled odkazů
Liu, Y. et al. 2007. BMC Cancer 7, 22.
Xu, K. et al. 2007. J. Biol. Chem. 282, 11347.
Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727.
Davidson, B. et al. 2004. Cancer 100, 2139.
Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510.
Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113.
He, Z. et al. 2003. Nat. Med. 9, 225.
He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600.
Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136.
Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221.
Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31.
Zhu, J. et al. 2002. Cell 111, 867.
Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993.
Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165.
Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331.
Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202.
Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863.
Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073.
Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision22-June-2011 RFH
SynonymsPC cell-derived growth factor (PCDGF)
DescriptionRecombinant, mouse progranulin, consisting of amino acids 18-589, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. Progranulin is an ubiquitously expressed, secreted glycoprotein that is involved in regulation of cell proliferation.
FormLyophilized
FormulationLyophilized from 0.2 µm filtered PBS.
Purity≥90% by SDS-PAGE
ContaminantsEndotoxin: ≤1.0 EU/µg protein
Biological activitySignificantly enhances neurite outgrowth of E18 rat embryonic cortical neurons using 4-16 µg/ml progranulin immobilized on nitrocelluose-coated microplates.
SolubilityReconstitute to 250 µg/ml with sterile PBS.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesLiu, Y. et al. 2007. BMC Cancer 7, 22.
Xu, K. et al. 2007. J. Biol. Chem. 282, 11347.
Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727.
Davidson, B. et al. 2004. Cancer 100, 2139.
Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510.
Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113.
He, Z. et al. 2003. Nat. Med. 9, 225.
He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600.
Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136.
Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221.
Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31.
Zhu, J. et al. 2002. Cell 111, 867.
Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993.
Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165.
Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331.
Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202.
Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863.
Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073.
Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.