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529574 PP3 - CAS 5334-30-5 - Calbiochem

529574
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
5334-30-5C₁₁H₉N₅
Description
Overview

This product has been discontinued.



A negative control for the Src family protein tyrosine kinase inhibitor PP2 (Cat. No. 529573). However, it inhibits the activity of EGFR kinase (IC50 = 2.7 µM).

Catalogue Number529574
Brand Family Calbiochem®
Synonyms4-Amino-7-phenylpyrazol[3,4-d]pyrimidine
References
ReferencesTraxler, P., et al. 1997. J. Med. Chem. 40, 3601.
Product Information
CAS number5334-30-5
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₁H₉N₅
Chemical formulaC₁₁H₉N₅
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationPP3, CAS 5334-30-5, is a negative control for the Src family protein tyrosine kinase inhibitor PP2 (Cat. No. 529573). However, it inhibits the activity of EGFR kinase (IC50 = 2.7 µM).
Biological Information
Primary TargetEGFR kinase
Primary Target IC<sub>50</sub>2.7 µM against EGFR kinase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
529574 0

Documentation

PP3 - CAS 5334-30-5 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

PP3 - CAS 5334-30-5 - Calbiochem Certificates of Analysis

TitleLot Number
529574

References

Přehled odkazů
Traxler, P., et al. 1997. J. Med. Chem. 40, 3601.

Brochure

Title
Bulk Product Guide

Citations

Název
  • Ellen J. Tisdale and Cristina R. Artalejo. 2006. Journal of Biological Chemistry 281, 8436.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision27-August-2008 RFH
    Synonyms4-Amino-7-phenylpyrazol[3,4-d]pyrimidine
    DescriptionA negative control for the Src family of protein tyrosine kinase inhibitor PP2 (Cat. No. 529573); however, it inhibits the activity of EGFR kinase (IC50 = 2.7 µM).
    FormOff-white solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number5334-30-5
    Chemical formulaC₁₁H₉N₅
    Structure formulaStructure formula
    Purity≥95% by HPLC
    SolubilityDMSO. Further dilute with aqueous buffers just prior to use.
    Storage -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
    Toxicity Standard Handling
    ReferencesTraxler, P., et al. 1997. J. Med. Chem. 40, 3601.
    Citation
  • Ellen J. Tisdale and Cristina R. Artalejo. 2006. Journal of Biological Chemistry 281, 8436.