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494128 Ochratoxin A - CAS 303-47-9 - Calbiochem

Ochratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs).

Ochratoxin A - CAS 303-47-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: OTA, Ochratoxin A, Aspergillus ochraceus

494128
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
303-47-9C₂₀H₁₈ClNO₆

Products

Katalogové čísloBalení ks/bal.
494128-1MG Skleněná láhev 1 mg
Description
OverviewOchratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs). OTA is indicated to play a role in down-regulating the expression of protective enzymes against oxidative stress. It is known to accumulate in several tissues of the body but is primarily localized in the kidney where it impairs proximal tubular functions, and thereby causes nephrotoxicity, glucosuria, enzymuria, and a decrease in the transport of para-aminohippuric acid (PAH). It also acts as an immunosuppressant and as a potent teratogen and carcinogen.
Catalogue Number494128
Brand Family Calbiochem®
SynonymsOTA, Ochratoxin A, Aspergillus ochraceus
References
ReferencesAnzai, N., et al. 2010. Toxins 2, 1381.
Chopra, M., et al. 2010. Cell Biol. Toxicol. 26, 239.
Luhe, A., et al. 2002. Tox. Sci. 73, 315.
Dirheimer, G., et al. 1991. IARC Swci Publ. 115, 171.
Product Information
CAS number303-47-9
FormOff-white powder
Hill FormulaC₂₀H₁₈ClNO₆
Chemical formulaC₂₀H₁₈ClNO₆
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥97% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 28-38-60-61

Very toxic if swallowed.
Irritating to skin.
May impair fertility.
May cause harm to the unborn child.
S PhraseS: 24/25-36/37/39-45

Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
494128-1MG 04055977272864

Documentation

Ochratoxin A - CAS 303-47-9 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Ochratoxin A - CAS 303-47-9 - Calbiochem Certificates of Analysis

TitleLot Number
494128

References

Přehled odkazů
Anzai, N., et al. 2010. Toxins 2, 1381.
Chopra, M., et al. 2010. Cell Biol. Toxicol. 26, 239.
Luhe, A., et al. 2002. Tox. Sci. 73, 315.
Dirheimer, G., et al. 1991. IARC Swci Publ. 115, 171.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-October-2016 JSW
SynonymsOTA, Ochratoxin A, Aspergillus ochraceus
DescriptionOchratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs). OTA is indicated to play a role in down-regulating the expression of protective enzymes against oxidative stress. It is known to accumulate in several tissues of the body but is primarily localized in the kidney where it impairs proximal tubular functions, and thereby causes nephrotoxicity, glucosuria, enzymuria, and a decrease in the transport of para-aminohippuric acid (PAH). It also acts as an immunosuppressant and as a potent teratogen and carcinogen.
FormOff-white powder
Intert gas (Yes/No) Packaged under inert gas
CAS number303-47-9
Chemical formulaC₂₀H₁₈ClNO₆
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO (50 mg/ml; nearly colorless solution)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Highly Toxic & Carcinogenic / Teratogenic
ReferencesAnzai, N., et al. 2010. Toxins 2, 1381.
Chopra, M., et al. 2010. Cell Biol. Toxicol. 26, 239.
Luhe, A., et al. 2002. Tox. Sci. 73, 315.
Dirheimer, G., et al. 1991. IARC Swci Publ. 115, 171.