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533998 Mitotic Tracker Probe, CDy6 - Calbiochem

A cell-permeable, photostable fluorescent probe for real-time imaging of lysosomal dynamics in proliferating cells undergoing mitosis.

Mitotic Tracker Probe, CDy6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (E)-7-(3,5-di-tert-Butyl-2-methoxystyryl)-3-(3-(2-(dimethylamino)ethylamino)-3-oxopropyl)-5,5-difluoro-9-methyl-5H-dipyrrolo[1,2-c:1ʹ,2ʹ-f][1,3,2]diazaborinin-4-ium-5-uide, Lysosomal Tracker Probe, CDy6

533998
  
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Přehled

Replacement Information

Tabulka spec. kláve

Empirical Formula
C₃₄H₄₇BF₂N₄O₂
Description
OverviewA cell-permeable, photostable, bodipy-derived fluorescent probe that can be used for real-time imaging of lysosomal dynamics in proliferating cells undergoing mitosis. Undergoes rapid re-localization from cytoplasm to nucleus during cell division, but does not interfere with cell cycle. Displays a sharp increase in intensity during mitosis and its fluorescence displays high sensitivity to acidic environment (pH 2-4). Can also be used for time-dependent whole-body in vivo imaging of tumor xenografts (CDy6 stained HeLa cells, s.c.) in BALB/c nude mice up to 21 days. Exhibits greater brightness, higher photostability, and significantly reduced toxicity when compared to LysoTracker Red, LysoTracker Green, LysoSensor Green and HOE33342. Abs max: 570 nm; Em max: 585 with a quantum yield of 0.89.

Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.
Catalogue Number533998
Brand Family Calbiochem®
Synonyms(E)-7-(3,5-di-tert-Butyl-2-methoxystyryl)-3-(3-(2-(dimethylamino)ethylamino)-3-oxopropyl)-5,5-difluoro-9-methyl-5H-dipyrrolo[1,2-c:1ʹ,2ʹ-f][1,3,2]diazaborinin-4-ium-5-uide, Lysosomal Tracker Probe, CDy6
References
ReferencesJeong, Y.M., et al. 2015. Chem. Biol. 22, 299.
Product Information
FormDark purple powder
Hill FormulaC₃₄H₄₇BF₂N₄O₂
Chemical formulaC₃₄H₄₇BF₂N₄O₂
ReversibleY
Quality LevelMQ100
Applications
Biological Information
Primary Targetcytoplasm
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Emission max.
Excitation max.
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C). Store in a dark vial, protected from light.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
533998 0

Documentation

Mitotic Tracker Probe, CDy6 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Přehled odkazů
Jeong, Y.M., et al. 2015. Chem. Biol. 22, 299.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision09-December-2016 JSW
Synonyms(E)-7-(3,5-di-tert-Butyl-2-methoxystyryl)-3-(3-(2-(dimethylamino)ethylamino)-3-oxopropyl)-5,5-difluoro-9-methyl-5H-dipyrrolo[1,2-c:1ʹ,2ʹ-f][1,3,2]diazaborinin-4-ium-5-uide, Lysosomal Tracker Probe, CDy6
DescriptionA cell-permeable, photostable, bodipy-derived fluorescent probe that can be used for real-time imaging of lysosomal dynamics in proliferating cells undergoing mitosis. Undergoes rapid re-localization from cytoplasm to nucleus during cell division, but does not interfere with cell cycle. Displays a sharp increase in intensity during mitosis and its fluorescence displays high sensitivity to acidic environment (pH 2-4). Can also be used for time-dependent whole-body in vivo imaging of tumor xenografts (CDy6 stained HeLa cells, s.c.) in BALB/c nude mice up to 21 days. Exhibits greater brightness, higher photostability, and significantly reduced toxicity when compared to LysoTracker Red, LysoTracker Green, LysoSensor Green and HOE33342. Abs max: 570 nm; Em max: 585 with a quantum yield of 0.89.
FormDark purple powder
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₃₄H₄₇BF₂N₄O₂
Purity≥98% by HPLC
SolubilityDMSO (10 mg/ml). Use only fresh, anhydrous DMSO for reconstitution.
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C). Store in a dark vial, protected from light.
Toxicity Standard Handling
ReferencesJeong, Y.M., et al. 2015. Chem. Biol. 22, 299.