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FCMAB168P Milli-Mark Anti-CD3 -PE Antibody, clone UCHT1

Milli-Mark Anti-CD3 -PE Antibody, clone UCHT1 is an antibody against CD3 for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P07766
FCMAB168P
100 tests  
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Tabulka spec. kláve

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMPhycoerythrinMonoclonal Antibody
Description
Catalogue NumberFCMAB168P
Trade Name
  • Milli-Mark
DescriptionMilli-Mark Anti-CD3 -PE Antibody, clone UCHT1
Alternate Names
  • T-cell receptor
Background InformationHuman TCR/CD3 is a complex structure on the lymphocyte surface. It consists of the TCR alpha beta or TCR gamma delta heterodimer and the associated CD3 complex. The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains, gamma, delta, epsilon. and zeta. Three different dimers, gamma epsilon, delta epsilon, and zeta zeta, constitute the CD3 complex. The MW of CD3epsilon is 20 000 (Campana, 1987). CD3 is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocyles, the CD3 antigen is predominantly detected on the cell surface (Swerdlow, 1988; Beverley, 1981). The majority of T cell neoplasms also expresses CD3, but it is absent from non-T-cell lymphoid malignancies (McMichael, 1987). Consistent with the pattern of synthesis of the antigen in normal thymocytes, the earliest site detectable within neoplastic cells is the cell cytoplasm (Swerdlow, 1988).
References
Product Information
FormatPhycoerythrin
Control
  • Human Lymphocytes
PresentationPurified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
Quality LevelMQ100
Applications
ApplicationMilli-Mark Anti-CD3 -PE Antibody, clone UCHT1 is an antibody against CD3 for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenHuman infant thymocytes and lymphocytes from a patient with Sézary disease.
CloneUCHT1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityAntibody recognizes Human CD3 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight 20 kDa (Campana, 1987)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using Human Lymphocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
FCMAB168P 04053252746321

Documentation

Milli-Mark Anti-CD3 -PE Antibody, clone UCHT1 MSDS

Title

Safety Data Sheet (SDS) 

Milli-Mark Anti-CD3 -PE Antibody, clone UCHT1 Certificates of Analysis

TitleLot Number
Milli-Mark Anti-CD3 -PE, clone UCHT1 - 2106922 2106922
Milli-Mark Anti-CD3 -PE, clone UCHT1 - NRG1762703 NRG1762703
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 - 3288478 3288478
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 - 3906939 3906939
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 - 4109225 4109225
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 -2853596 2853596
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 -2854160 2854160
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 - 2376457 2376457
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 - 2384750 2384750
Milli-Mark™ Anti-CD3 -PE, clone UCHT1 - 2390565 2390565
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Kategorie

Life Science Research > Antibodies and Assays > Primary Antibodies