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105020 L-leucin

Přehled

Replacement Information

Tabulka spec. kláve

CAS #EC NumberHill FormulaMolar MassGrade Value
61-90-5200-522-0C₆H₁₃NO₂131.17 g/molPh Eur,ChP,JP,USP

Products

Katalogové čísloBalení ks/bal.
1050201000 Plastová láhev 1 kg
1050209010 Plastový sud 10 kg
Description
Catalogue Number105020
SynonymsLeu
References
Product Information
CAS number61-90-5
EC number200-522-0
GradePh Eur,ChP,JP,USP
Hill FormulaC₆H₁₃NO₂
Molar Mass131.17 g/mol
HS Code2922 49 90
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.17 g/cm3 (20 °C)
Melting Point293 °C (rozklad)
pH value5.5 - 6.5 (20 g/l, H₂O, 20 °C)
Vapor pressure<1 hPa (20 °C)
Bulk density300 - 400 kg/m3
Solubility18.9 g/l
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSOH2850000
Storage class10 - 13 Ostatní kapalné a tuhé látky
WGKWGK 1 látka mírně ohrožující vody
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageSkladovat od +2°C až +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
Identity (IR-spectrum)passes test
Identity (specific rotation)passes test
Identity (TLC)passes test
Appearancewhite to almost white, crystalline powder or shiny flakes
Appearance of solution (50 g/l; hydrochloric acid 1 mol/l)clear and not more intense in color than reference solution BY₆
Transmittance of solution (10 g/l, water)≥ 98.0 %
Spec. rotation (α 20/D, 40 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+14.5 to +16.5
Spec. rotation (α 25/D, 40 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+14.9 to +17.3
Spec. rotation (α 20/D, 40 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+14.9 to +16.0
pH (10 g/l, CO₂-free water)5.5 - 6.5
Acidity (10 g/l, water)5.5 - 6.5
Chloride (Cl)≤ 200 ppm
Sulfate (SO₄)≤ 200 ppm
Heavy metals (as Pb)≤ 10 ppm
Fe (Iron)≤ 10 ppm
As (Arsenic)≤ 1 ppm
Other amino acids (TLC)≤ 0.5 %
Related Compounds, total (TLC)≤ 0.5 %
Related substances (TLC)passes test
Related compounds (HPLC) (Isoleucine)≤ 0.8 %
Related compounds (HPLC) (Any unspecified impurity)≤ 0.2 %
Related compounds (HPLC) (Total unspecified impurities)≤ 1.0 %
Ninhydrin-positive substances (LC) (impurity A (570 nm))≤ 0.8 %
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)≤ 1.0 %
Residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash (600 °C)≤ 0.1 %
Loss on drying (105 °C; 3 h)≤ 0.20 %
Bacterial endotoxins≤ 3.0 I.U./g
Microbiological test (total aerobic microbial count (TAMC))≤ 10²
Microbiological test (total yeast and mould count (TYMC))≤ 10¹
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., JP, USP
Global Trade Item Number
Katalogové číslo GTIN
1050201000 04022536986364
1050209010 04022536986098

Documentation

Material Qualification Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

L-leucin MSDS

Title

Safety Data Sheet (SDS) 

L-leucin Certificates of Analysis

Katalogové číslo BaleníSpecifikaceČíslo šarže
1050201000 Plastová láhevSpecifikující dokument ve formátu PDF
1050209010 Plastový sudSpecifikující dokument ve formátu PDF

Certificates

Title