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506271 Ketanserin Tartrate - CAS 83846-83-7 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5-HT2A Serotonin Receptor Antagonist, Ketanserin, R 41 468

Primary Target: 5-HT2A
506271
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
83846-83-7C₂₂H₂₂FN₃O₃·C₄H₆O₆

Products

Katalogové čísloBalení ks/bal.
5.06271.0001 Skleněná láhev 50 mg
Description
OverviewA selective 5-HT2A serotonin receptor antagonist with weak adrenergic receptor blocking properties. Strong affinity for 5-HT2AR (Ki = 1.49 nM) relative to other family members like 5-HT2BR (Ki = 740 nM) and 5-HT2CR (Ki = 59 nM). Often used in conjunction with SB 206553 to distinguish 5-HT2AR and 5-HT2CR activity.
Catalogue Number506271
Brand Family Calbiochem®
Synonyms5-HT2A Serotonin Receptor Antagonist, Ketanserin, R 41 468
References
ReferencesRos, R. et al. 2013. PNAS. 110, 348.
Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
Aloyo, V. J. and Harvey, J. A. 2000. Eur. J. Pharmacol. 406, 163.
Leysen, J. E. et al. 1981. Life Sci. 28, 1015.
Product Information
CAS number83846-83-7
FormWhite solid
Hill FormulaC₂₂H₂₂FN₃O₃·C₄H₆O₆
Chemical formulaC₂₂H₂₂FN₃O₃·C₄H₆O₆
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target5-HT2A
Primary Target K<sub>i</sub>1.49 nM
Purity≥97% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 25

Toxic if swallowed.
S PhraseS: 46

If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
5.06271.0001 04055977243192

Documentation

Ketanserin Tartrate - CAS 83846-83-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Přehled odkazů
Ros, R. et al. 2013. PNAS. 110, 348.
Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
Aloyo, V. J. and Harvey, J. A. 2000. Eur. J. Pharmacol. 406, 163.
Leysen, J. E. et al. 1981. Life Sci. 28, 1015.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-September-2013 JSW
Synonyms5-HT2A Serotonin Receptor Antagonist, Ketanserin, R 41 468
DescriptionA selective 5-HT2A serotonin receptor antagonist with weak adrenergic receptor blocking properties. Strong affinity for 5-HT2AR (Ki = 1.49 nM) relative to other family members like 5-HT2BR (Ki = 740 nM) and 5-HT2CR (Ki = 59 nM). Often used in conjunction with SB 206553 to distinguish 5-HT2AR and 5-HT2CR activity.
FormWhite solid
CAS number83846-83-7
Chemical formulaC₂₂H₂₂FN₃O₃·C₄H₆O₆
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Toxic
ReferencesRos, R. et al. 2013. PNAS. 110, 348.
Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
Aloyo, V. J. and Harvey, J. A. 2000. Eur. J. Pharmacol. 406, 163.
Leysen, J. E. et al. 1981. Life Sci. 28, 1015.