Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

539744 InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I - Calbiochem

The InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I controls the biological activity of InhibitorSelect™. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
539744
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information
Description
Overview

This product has been discontinued.



The InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I consists of 80, well-characterized, cell-permeable, potent and reversible protein kinase inhibitors; the majority of which are ATP-competitive. They are supplied in a convenient 96-well plate format at a concentration of 10 mM in DMSO. The inhibitors in this library will be useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications.
Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
Catalogue Number539744
Brand Family Calbiochem®
Application Data

** Total higher than 80, as some inhibitors target kinases in other branches as well TK: Tyrosine Kinase Group AGC: PKA, PKG, and PKC Containing Group TKL: Tyrosine Kinase-Like Group
References
Product Information
Form96-well plate
FormulationAll of the inhibitors, except for one, are supplied at a concentration of 10 mM in DMSO (50 µl/well).
Hygroscopic Hygroscopic
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/38-68

Irritating to eyes and skin.
Possible risks of irreversible effects.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Harmful
Storage ≤ -70°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
539744 0

Documentation

InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I - Calbiochem Certificates of Analysis

TitleLot Number
539744

Citations

Název
  • Hou, P., et al. 2013. Science 341, 651.
  • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
  • Yinghong Gao, et al. 2013. Biochem. J. in press.
  • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
  • Cohen, T., et al. 2012. Biochem. J. in press.
  • Wakatsuki, S., 2011. Nature Cell Biol. 13, 1415.
  • Elkaim, J., 2012. Biochem. J. in press.
  • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
  • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
  • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
  • Donovi, D., et al. 2010. Biochem Soc Trans. 38, 1067.
  • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
  • Li, Tao, et al. 2010. Anal. Chem. 82, 3067.
  • Cameron A. J. M., et al. 2009., Nature Structural & Molecular Biology 16, 624.
  • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 132 2518.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision11-September-2012 JSW
    Application Data

    ** Total higher than 80, as some inhibitors target kinases in other branches as well TK: Tyrosine Kinase Group AGC: PKA, PKG, and PKC Containing Group TKL: Tyrosine Kinase-Like Group
    DescriptionThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library I consists of 80, well-characterized protein kinase inhibitors, the majority of which are cell-permeable and ATP-competitive. The library is useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications. Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
    Form96-well plate
    FormulationAll of the inhibitors, except for one, are supplied at a concentration of 10 mM in DMSO (50 µl/well).
    Intert gas (Yes/No) Packaged under inert gas
    Storage Protect from light
    ≤ -70°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
    Toxicity Harmful
    Citation
  • Hou, P., et al. 2013. Science 341, 651.
  • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
  • Yinghong Gao, et al. 2013. Biochem. J. in press.
  • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
  • Cohen, T., et al. 2012. Biochem. J. in press.
  • Wakatsuki, S., 2011. Nature Cell Biol. 13, 1415.
  • Elkaim, J., 2012. Biochem. J. in press.
  • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
  • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
  • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
  • Donovi, D., et al. 2010. Biochem Soc Trans. 38, 1067.
  • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
  • Li, Tao, et al. 2010. Anal. Chem. 82, 3067.
  • Cameron A. J. M., et al. 2009., Nature Structural & Molecular Biology 16, 624.
  • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 132 2518.
    		•