Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

559397 InSolution™ SB 202190 - CAS 152121-30-7 - Calbiochem

559397
Purchase on Sigma-Aldrich

Přehled

Tabulka spec. kláve

CAS #Empirical Formula
152121-30-7C₂₀H₁₄FN₃O

Products

Katalogové čísloBalení ks/bal.
559397-1ML Skleněná láhev 1 ml
Description
Catalogue Number559397
Brand Family Calbiochem®
SynonymsInSolution™ p38 MAP Kinase Inhibitor II
References
ReferencesAjizian, S.J., et al. 1999. J. Infect. Dis. 179, 939.
Singh, R.P., et al. 1999. J. Biol. Chem. 274, 19593.
Wang, S.W., et al. 1999. Inflamm. Res. 48, 533.
Gallagher, T.F., et al. 1997. Bioorg. Med. Chem. 5, 49.
Jiang, Y., et al. 1996. J. Biol. Chem. 271, 17920.
Kramer, R.M., et al. 1996. J. Biol. Chem. 271, 27723.
Li, Z., et al. 1996. Biochem. Biophys. Res. Commun. 228, 334.
Lee, L.C., et al. 1994. Nature 372, 739.
Product Information
CAS number152121-30-7
ATP CompetitiveY
FormLiquid
FormulationA 1 mg/ml solution of SB 202190 (Cat. No. 559388) in anhydrous DMSO.
Hill FormulaC₂₀H₁₄FN₃O
Chemical formulaC₂₀H₁₄FN₃O
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetP38β
Primary Target IC<sub>50</sub>16 nM
Primary Target K<sub>i</sub>16 nM; 350 nM against the kinase activity of p38β; 280 nM against p38 phosphorylation of activating transcription factor 2 (ATF-2)
Purity≥98% by HPLC
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Cell permeableY
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Katalogové číslo GTIN
559397-1ML 04055977192629