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504746 Idazoxan Hydrochloride - CAS 79944-56-2 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride, RX781094, Idazoxa, α₂-Adrenoceptor Antagonist, Idazoxan Hydrochloride

Primary Target: →₂-adrenoceptor
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Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
79944-56-2C₁₁H₁₂N₂O₂ • HCl
Description
Overview

This product has been discontinued.



A non-selective antagonist for α2-adrenoceptors (pKi = 8.01, 7.43, and 7.7 for α2A, α2B, and α2C receptors respectively) and imidazoline receptors. (pKi = 5.90, 7.22 for I1 and I2, receptors respectively). Widely used in studying functions of the nervous systems, such as learning and memory, decision making, reward, attention, addiction, depression, and schizophrenia related to the adrenergic receptors, and blood pressure regulation, pain modulation, and neuroprotection related to the imidazoline receptors.
Catalogue Number504746
Brand Family Calbiochem®
Synonyms2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride, RX781094, Idazoxa, α₂-Adrenoceptor Antagonist, Idazoxan Hydrochloride
References
ReferencesHumpston, S., et al. 2013. J. of Psychopharmacology, 27, 213.
Dabir, l., 1986. J.Pharmacol. 17, 113.
Michel, M., et al. 1992. TIPS 13, 369.
Eglen, R., et al. 1998. TiPS 19, 381.
Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
Gadie, B., 1984. Br J Pharmacol. 83, 707.
Product Information
CAS number79944-56-2
FormWhite powder
Hill FormulaC₁₁H₁₂N₂O₂ • HCl
Chemical formulaC₁₁H₁₂N₂O₂ • HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target→₂-adrenoceptor
Purity≥98% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 25

Toxic if swallowed.
S PhraseS: 22-36-45

Do not breathe dust.
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +15°C to +30°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
504746 0

Documentation

Idazoxan Hydrochloride - CAS 79944-56-2 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Přehled odkazů
Humpston, S., et al. 2013. J. of Psychopharmacology, 27, 213.
Dabir, l., 1986. J.Pharmacol. 17, 113.
Michel, M., et al. 1992. TIPS 13, 369.
Eglen, R., et al. 1998. TiPS 19, 381.
Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
Gadie, B., 1984. Br J Pharmacol. 83, 707.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision31-May-2013 JSW
Synonyms2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride, RX781094, Idazoxa, α₂-Adrenoceptor Antagonist, Idazoxan Hydrochloride
DescriptionA non-selective antagonist for ?2-adrenoceptors (pKi = 8.01, 7.43, and 7.7 for ?2A, ?2B, and ?2C receptors respectively) and imidazoline receptors. (pKi = 5.90, 7.22 for I1 and I2, receptors respectively). Widely used in studying functions of the nervous systems, such as learning and memory, decision making, reward, attention, addiction, depression, and schizophrenia related to the adrenergic receptors, and blood pressure regulation, pain modulation, and neuroprotection related to the imidazoline receptors.
FormWhite powder
CAS number79944-56-2
Chemical formulaC₁₁H₁₂N₂O₂ • HCl
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (50 mg/ml)
Storage Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Toxic
ReferencesHumpston, S., et al. 2013. J. of Psychopharmacology, 27, 213.
Dabir, l., 1986. J.Pharmacol. 17, 113.
Michel, M., et al. 1992. TIPS 13, 369.
Eglen, R., et al. 1998. TiPS 19, 381.
Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
Gadie, B., 1984. Br J Pharmacol. 83, 707.