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CC065 Human Tenascin-C Purified Protein

CC065
100 µg  
Purchase on Sigma-Aldrich

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Replacement Information

Tabulka spec. kláve

Key Applications
PC, CULT
Description
Catalogue NumberCC065
ReplacesCC066
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionHuman Tenascin-C Purified Protein
OverviewPurified Human Tenascin-C Protien. Tenascin is known to: 1) play an active role in development of central nervous system and mesenchymal-derived organs; 2) exist in vasculature of tumors in adults; and 3) function in cell adhesion. By SDS-PAGE analysis, the protein migrates around 280-300kD.
Alternate Names
  • TN-C
  • Tenascin
  • Hexabrachion
  • Cytotactin
  • Neuronectin
References
Product Information
HS Code3502 90 90
PresentationPurified protein supplied as a liquid in PBS containing no preservatives.
Quality LevelMQ100
Applications
Key Applications
  • Positive Control
  • Cell Culture
Application NotesCell adhesion assays.

Optimal working dilutions must be determined by end user.
Biological Information
Concentration0.1 mg/mL
Purity> 97% pure by SDS-PAGE
SourceHuman glioma cell line (U251).
Entrez Gene Number
Gene Symbol
  • TNC
  • Hexabrachion
  • HXB
  • GMEM
  • TN
  • Neuronectin
  • Tenascin-C
  • MGC167029
  • JI
  • TN-C
  • Cytotactin
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P24821 # Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
SIZE: 2201 amino acids; 240866 Da
SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
PTM: N-glycosylated (By similarity).
SIMILARITY: SwissProt: P24821 ## Belongs to the tenascin family. & Contains 15 EGF-like domains. & Contains 1 fibrinogen C-terminal domain. & Contains 15 fibronectin type-III domains.
Stem Cell Type
  • Human Embryonic Stem Cells
  • Mesenchymal Stem Cells
  • Neural Stem Cells
  • Hematopoietic Stem Cells
  • Epithelial Cells
  • Pancreatic Stem Cells
  • Induced Pluripotent Stem Cells
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -70ºC for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
CC065 04053252671982

Documentation

Human Tenascin-C Purified Protein MSDS

Title

Safety Data Sheet (SDS) 

Human Tenascin-C Purified Protein Certificates of Analysis

TitleLot Number
HUMAN TENASCIN - C 2483223
HUMAN TENASCIN - C PURIFIED PROTEIN - 2137988 2137988
HUMAN TENASCIN - C PURIFIED PROTEIN - 2375504 2375504
HUMAN TENASCIN - C PURIFIED PROTEIN - 2390408 2390408
HUMAN TENASCIN - C PURIFIED PROTEIN - 2426461 2426461
HUMAN TENASCIN - C PURIFIED PROTEIN - 2450673 2450673
HUMAN TENASCIN - C - 3209134 3209134
HUMAN TENASCIN - C - 3243036 3243036
HUMAN TENASCIN - C - 3243037 3243037
HUMAN TENASCIN - C - 3305886 3305886

Data Sheet

Title
HUMAN TENASCIN - C PURIFIED PROTEIN