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373386 Hh Signaling Pathway Modulators

Hh Signaling Pathway Modulators MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
373386
  
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Přehled

Replacement Information
Description
Overview

This product has been discontinued.



A panel containing 14 potent, selective and cell-permeable antagonists, inhibitors and agonists that are useful for the study of the Hh (Hedgehog) signaling pathway: 5 mg of βARK1 Inhibitor (Cat. No. 182200), 100 µg of Cyclopamine-KAAD (Cat. No. 239804), 25 mg of Fluvastatin, Sodium Salt (Cat. No. 344095), 1 mg of GSK-3 Inhibitor IX; BIO (Cat. No. 361550), 1 mg of H-89, Dihydrochloride (Cat. No. 371963), 10 mg of Hh Signaling Antagonist XIV; SANT-2 (Cat. No. 373273), 10 mg of Hh Signaling Antagonist XII; HPI-1 (Cat. No. 373275), 10 mg of Hh Signaling Antagonist XIII; HPI-3 (Cat. No. 373276), 5 mg of Hh/Gli Antagonist; GANT61 (Cat. No. 373401), 5 mg of Hh Signaling Antagonist VII; JK184 (Cat. No. 373385), 5 mg of IC261 (Cat. No. 400090), 5 mg of MG-132 (Cat. No. 474790), 5 mg of Purmorphamine (Cat. No. 540220) and 1 mg of Smoothened Agonist; SAG (Cat. No. 566660). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.
Catalogue Number373386
Brand Family Calbiochem®
Application Data
References
ReferencesPeukert, S. and Miller-Moslin, K., 2010. Chem. Med. Chem. 6, 500.
Tremblay, M.R., et al. 2010. Curr. Opin. Chem. Biol. 14, 428.
Scales, S.J. and de Sauvage, F. J., 2009. Trends. Pharmacol. Sci. 30, 303.
Jiang, J. and Hui, C.C., 2008. Dev. Cell 15, 801.
Lum, L. and Beachy, P.A, 2004. Science 304, 1755
Ingham, P.W. and McMohan, A.P., 2001. Genes Dev. 15, 3059.
Product Information
FormSolid
Hygroscopic Hygroscopic
Quality LevelMQ100
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22-36/38

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes and skin.
S PhraseS: 22-24/25-36/37/39-45

Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Harmful
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
373386 0

Documentation

Hh Signaling Pathway Modulators MSDS

Title

Safety Data Sheet (SDS) 

Hh Signaling Pathway Modulators Certificates of Analysis

TitleLot Number
373386

References

Přehled odkazů
Peukert, S. and Miller-Moslin, K., 2010. Chem. Med. Chem. 6, 500.
Tremblay, M.R., et al. 2010. Curr. Opin. Chem. Biol. 14, 428.
Scales, S.J. and de Sauvage, F. J., 2009. Trends. Pharmacol. Sci. 30, 303.
Jiang, J. and Hui, C.C., 2008. Dev. Cell 15, 801.
Lum, L. and Beachy, P.A, 2004. Science 304, 1755
Ingham, P.W. and McMohan, A.P., 2001. Genes Dev. 15, 3059.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-March-2011 RFH
Application Data
DescriptionA panel containing 14 potent, selective and cell-permeable antagonists, inhibitors and agonists that are useful for the study of the Hh (Hedgehog) signaling pathway. The panel contains the following inhibitors and 15 ml anhydrous DMSO for reconstitution:
FormSolid
Intert gas (Yes/No) Packaged under inert gas
SolubilityDMSO (supplied). Please refer to information provided on the CD for reconstitution of individual inhibitors.
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Toxicity Harmful
ReferencesPeukert, S. and Miller-Moslin, K., 2010. Chem. Med. Chem. 6, 500.
Tremblay, M.R., et al. 2010. Curr. Opin. Chem. Biol. 14, 428.
Scales, S.J. and de Sauvage, F. J., 2009. Trends. Pharmacol. Sci. 30, 303.
Jiang, J. and Hui, C.C., 2008. Dev. Cell 15, 801.
Lum, L. and Beachy, P.A, 2004. Science 304, 1755
Ingham, P.W. and McMohan, A.P., 2001. Genes Dev. 15, 3059.