Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

345670 Galanthamine, Hydrobromide - CAS 69353-21-5 - Calbiochem

A competitive and reversible inhibitor of acetylcholinesterase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Nivalin, HBr

Primary Target: Acetylcholinesterase
345670
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
69353-21-5C₁₇H₂₁NO₃ · HBr

Products

Katalogové čísloBalení ks/bal.
345670-20MG 20 mg
Description
OverviewA competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
Catalogue Number345670
Brand Family Calbiochem®
SynonymsNivalin, HBr
References
ReferencesPilger, C., et al. 2001. J. Mol. Graph. Model 19, 288.
Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.
Southan, G.J., et al. 1996. Br. J. Pharmacol. 117, 619.
Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.
Product Information
CAS number69353-21-5
ATP CompetitiveY
FormWhite solid
Hill FormulaC₁₇H₂₁NO₃ · HBr
Chemical formulaC₁₇H₂₁NO₃ · HBr
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetAcetylcholinesterase
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSDF8075000
Safety Information
R PhraseR: 25

Toxic if swallowed.
S PhraseS: 22-36/37/39-45

Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
345670-20MG 04055977194494

Documentation

Galanthamine, Hydrobromide - CAS 69353-21-5 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Galanthamine, Hydrobromide - CAS 69353-21-5 - Calbiochem Certificates of Analysis

TitleLot Number
345670

References

Přehled odkazů
Pilger, C., et al. 2001. J. Mol. Graph. Model 19, 288.
Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.
Southan, G.J., et al. 1996. Br. J. Pharmacol. 117, 619.
Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.

Brochure

Title
Alzheimer's Disease Brochure & Technical Guide
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-March-2010 RFH
SynonymsNivalin, HBr
DescriptionCholinesterase antagonist. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats.
FormWhite solid
CAS number69353-21-5
RTECSDF8075000
Chemical formulaC₁₇H₂₁NO₃ · HBr
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml), Ethanol (1 mg/ml) or H₂O (1 mg/ml)
Storage Protect from moisture
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Toxic
Merck USA index14, 4340
ReferencesPilger, C., et al. 2001. J. Mol. Graph. Model 19, 288.
Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.
Southan, G.J., et al. 1996. Br. J. Pharmacol. 117, 619.
Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.