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365252 Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem

365252
  
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Tabulka spec. kláve

CAS #Empirical Formula
287935-76-6C₂₇H₂₆N₄O₄ · HCl
Description
Overview

This product has been discontinued.



A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of protein kinase C (IC50 = 4 nM for rat brain PKC). Inhibits protein kinase A (IC50 = 510 nM), protein kinase G (IC50 = 4.8 µM), and myosin light chain kinase (IC50 = 120 nM) at much higher concentrations.

Catalogue Number365252
Brand Family Calbiochem®
SynonymsMLCK Inhibitor III
References
ReferencesKleinschroth, J., et al. 1995. Bioorg. Med. Chem. Lett. 5, 55.
Product Information
CAS number287935-76-6
ATP CompetitiveY
FormAmber solid
Hill FormulaC₂₇H₂₆N₄O₄ · HCl
Chemical formulaC₂₇H₂₆N₄O₄ · HCl
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKC
Primary Target IC<sub>50</sub>4 nM against rat brain PKC
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
365252 0

Documentation

Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Gö 7874, Hydrochloride - CAS 287935-76-6 - Calbiochem Certificates of Analysis

TitleLot Number
365252

References

Přehled odkazů
Kleinschroth, J., et al. 1995. Bioorg. Med. Chem. Lett. 5, 55.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-April-2011 RFH
SynonymsMLCK Inhibitor III
DescriptionA cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of rat brain protein kinase C (IC50 = 4 nM) versus myosin light chain kinase (IC50 = 0.12 µM), protein kinase A (IC50 = 510 nM), and protein kinase G (IC50 = 4.8 µM).
FormAmber solid
CAS number287935-76-6
Chemical formulaC₂₇H₂₆N₄O₄ · HCl
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO (25 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesKleinschroth, J., et al. 1995. Bioorg. Med. Chem. Lett. 5, 55.