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341608 FGF Receptor Tyrosine Kinase Inhibitor - CAS 192705-79-6 - Calbiochem

The FGF Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 192705-79-6, controls the biological activity of FGF Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for

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MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-(2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butyl urea, PD 166866

341608
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Přehled

Tabulka spec. kláve

CAS #Empirical Formula
192705-79-6C₂₀H₂₄N₆O₃

Products

Katalogové čísloBalení ks/bal.
341608-5MG Plastová ampulka 5 mg
Přidat k oblíbeným položkám
Description
OverviewA cell-permeable pyridopyrimidinyl urea compound that acts a potent, ATP-competitive inhibitor of FGFR (IC50 = 60 nM using FGFR1) with excellent selectivity over PDGFRβ, EGFR, insulin receptor, and c-Src (IC50 > 50 µM).
Catalogue Number341608
Brand Family Calbiochem®
Synonyms1-(2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-tert-butyl urea, PD 166866
References
ReferencesPanek, R.L., et al. 1998. J. Pharm. Exp. Ther. 286, 569.
Hamby, J.M., et al. 1997. J. Med. Chem. 40, 2296.
Product Information
CAS number192705-79-6
FormOff-white solid
Hill FormulaC₂₀H₂₄N₆O₃
Chemical formulaC₂₀H₂₄N₆O₃
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity≥97% by HPLC
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Katalogové číslo GTIN
341608-5MG 04055977195217