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505026 DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: AMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX

Primary Target: AMPA
505026
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
2379-57-9C₈H₂N₄O₆Na₂

Products

Katalogové čísloBalení ks/bal.
5.05026.0001 Skleněná láhev 10 mg
Description
OverviewA potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.
Catalogue Number505026
Brand Family Calbiochem®
SynonymsAMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX
References
ReferencesLee, S., et al. 2010. J. Neurophysiol. 103, 1728.
Honor, T., et al. 1998. Science. 241, 701.
Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.
Product Information
CAS number2379-57-9
FormDark brown solid
Hill FormulaC₈H₂N₄O₆Na₂
Chemical formulaC₈H₂N₄O₆Na₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetAMPA
Primary Target IC<sub>50</sub>0.19 to 1.66 uM
Secondary targetGluK2
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
5.05026.0001 04055977263336

Documentation

DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem Certificates of Analysis

TitleLot Number
505026

References

Přehled odkazů
Lee, S., et al. 2010. J. Neurophysiol. 103, 1728.
Honor, T., et al. 1998. Science. 241, 701.
Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-July-2013 JSW
SynonymsAMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX
DescriptionA potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.
FormDark brown solid
CAS number2379-57-9
Chemical formulaC₈H₂N₄O₆Na₂
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesLee, S., et al. 2010. J. Neurophysiol. 103, 1728.
Honor, T., et al. 1998. Science. 241, 701.
Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.