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567727 D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem

A putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
567727
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
26993-30-6C₁₈H₃₈NO₅P

Products

Katalogové čísloBalení ks/bal.
567727-1MG Plastová ampulka 1 mg
Description
OverviewA putative second messenger that mobilizes calcium from intracellular stores via an IP3-independent pathway. Activates phospholipase D (PLD) and inhibits chemotactic motility and invasiveness of tumor cells. Also stimulates growth of quiescent Swiss/3T3 fibroblasts. Inhibits activation of caspases that cleave PARP and lamins during Fas- and ceramide-mediated apoptosis.
Catalogue Number567727
Brand Family Calbiochem®
References
ReferencesCuvillier, O., et al. 1998. J. Biol. Chem. 273, 2910.
Mattie, M., et al. 1994. J. Biol. Chem. 269, 3181.
Olivera, A. and Spiegel, S. 1993. Nature 365, 557.
Desai, N.N., et al. 1992. J. Biol. Chem. 267, 23122.
Sadahira, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 9686.
Product Information
CAS number26993-30-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₈H₃₈NO₅P
Chemical formulaC₁₈H₃₈NO₅P
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMobilizes calcium from intracellular stores
Purity≥95% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and evaporate under a stream of nitrogen. Store at -20°C. Prior to use, dissolve in 4 mg/ml BSA solution with vortexing. Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
567727-1MG 07790788051679

Documentation

D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

D-erythro-Sphingosine-1-phosphate - CAS 26993-30-6 - Calbiochem Certificates of Analysis

TitleLot Number
567727

References

Přehled odkazů
Cuvillier, O., et al. 1998. J. Biol. Chem. 273, 2910.
Mattie, M., et al. 1994. J. Biol. Chem. 269, 3181.
Olivera, A. and Spiegel, S. 1993. Nature 365, 557.
Desai, N.N., et al. 1992. J. Biol. Chem. 267, 23122.
Sadahira, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 9686.

Brochure

Title
Bioactive Lipids Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-September-2008 RFH
DescriptionA putative second messenger that mobilizes calcium from intracellular stores via an IP3 independent pathway. Activates phospholipase D and inhibits chemotactic motility and invasiveness of tumor cells. Also stimulates growth of quiescent Swiss 3T3 fibroblasts.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number26993-30-6
Chemical formulaC₁₈H₃₈NO₅P
Structure formulaStructure formula
Purity≥95% by TLC
SolubilityMethanol (0.5 mg/ml). Slight warming and vortexing may be required.
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and evaporate under a stream of nitrogen. Store at -20°C. Prior to use, dissolve in 4 mg/ml BSA solution with vortexing. Stock solutions are stable for up to 2 months at -20°C.
Toxicity Irritant
ReferencesCuvillier, O., et al. 1998. J. Biol. Chem. 273, 2910.
Mattie, M., et al. 1994. J. Biol. Chem. 269, 3181.
Olivera, A. and Spiegel, S. 1993. Nature 365, 557.
Desai, N.N., et al. 1992. J. Biol. Chem. 267, 23122.
Sadahira, Y., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 9686.