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204883 Complement C1-Esterase Inhibitor, Human

Complement C1-Esterase Inhibitor, Human, is a native, single-chain glycoprotein that is involved in regulation of complement, coagulation, fibrinolytic and contact systems of circulating plasma.

Complement C1-Esterase Inhibitor, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
204883
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Katalogové čísloBalení ks/bal.
204883-1MG Plastová ampulka 1 mg
Přidat k oblíbeným položkám
Description
OverviewNative, human C1-esterase. Single-chain glycoprotein present in normal human serum at 180 µg/ml. Involved in regulation of complement, coagulation, fibrinolytic and contact (kinin-forming) systems of circulating blood plasma. The only known inhibitor of activated C1r and C1s complement enzymes. The presence of either hereditary or acquired deficiencies of C1 inhibitor produce susceptibility to recurrent attacks of angioedema.
Catalogue Number204883
Brand Family Calbiochem®
References
ReferencesBowen, B., et al. 2001. Clin. Immunol. 98, 157.
Davis, A.E. 1988. Ann. Rev. Immunol. 6, 595.
Product Information
FormLiquid
FormulationIn PBS, pH 7.3, sterile-filtered through a 0.22 µm filter.
PreservativeNone
Quality LevelMQ100
Applications
Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
Biological Information
Biological activity≥80% of C1-esterase inhibitor will bind activated C1s.
Purity≥90% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
ContaminantsIgG, IgA, IgM, albumin, C3, C4, or ceruloplasmin: ≤trace amounts
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Katalogové číslo GTIN
204883-1MG 04055977219777