Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

218717 Casein Kinase II Inhibitor V, Quinalizarin - CAS 81-61-8 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,2,5,8-Tetrahydroxy-9,10-anthraquinone

218717
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
81-61-8C₁₄H₈O₆
Description
Overview

This product has been discontinued.



A cell-permeable hydroxylated anthraquinone compound that acts as a potent (IC50 = 110 nM), highly selective (IC50 >1µM against CK1 and 83 other kinases), and ATP-competitive (Ki = 50 nM) CK2 inhibitor with greater selectivity than TBB (Cat. Nos. 218697 and 218708) and DMAT (Cat. Nos. 218699 and 218706) against DYRK1a, PIM1/3, and HIPK2. Quinalizarin is about 4.3- and 1.9-fold more effective than TBB, respectively, in cellular CK2 activity inhibition and in apoptosis induction in Jurkat cell cultures.
Catalogue Number218717
Brand Family Calbiochem®
Synonyms1,2,5,8-Tetrahydroxy-9,10-anthraquinone
References
ReferencesCozza, G., et al. 2009. Biochem. J. 421, 387.
Product Information
CAS number81-61-8
FormDark red solid
Hill FormulaC₁₄H₈O₆
Chemical formulaC₁₄H₈O₆
Structure formula ImageStructure formula Image
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
218717 0

Documentation

Casein Kinase II Inhibitor V, Quinalizarin - CAS 81-61-8 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Casein Kinase II Inhibitor V, Quinalizarin - CAS 81-61-8 - Calbiochem Certificates of Analysis

TitleLot Number
218717

References

Přehled odkazů
Cozza, G., et al. 2009. Biochem. J. 421, 387.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-June-2010 RFH
Synonyms1,2,5,8-Tetrahydroxy-9,10-anthraquinone
DescriptionA cell-permeable hydroxylated anthraquinone compound that acts as a potent (IC50 = 110 nM), highly selective (IC50 >1µM against CK1 and 83 other kinases), and ATP-competitive (Ki = 50 nM) CK2 inhibitor with greater selectivity than TBB (Cat. Nos. 218697 and 218708) and DMAT (Cat. Nos. 218699 and 218706) against DYRK1a, PIM1/3, and HIPK2. Quinalizarin is about 4.3- and 1.9-fold more effective than TBB, respectively, in cellular CK2 activity inhibition and in apoptosis induction in Jurkat cell cultures.
FormDark red solid
Intert gas (Yes/No) Packaged under inert gas
CAS number81-61-8
Chemical formulaC₁₄H₈O₆
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (50 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Irritant
ReferencesCozza, G., et al. 2009. Biochem. J. 421, 387.