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217460 Cardiogenol C - CAS 671225-39-1 - Calbiochem

217460
  
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
671225-39-1C₁₃H₁₆N₄O₂
Description
Overview

This product has been discontinued.



A cell-permeable pyrimidine compound that potently induces the differentiation of ESCs (embryonic stem cells) into cardiomyocytes (EC50 = 100 nM) without significant cytotoxic effect even at concentrations as high as 25 µM. The induction of cardiomyogenesis by Cardiogenol C is much more efficient than that achieved by EBs (embryoid bodies) formation and DMSO treatment.

Catalogue Number217460
Brand Family Calbiochem®
Synonyms2-(4-Methoxyanilino)-4-(1-hydroxyethylamino)pyrimidine
References
ReferencesWu, X., et al. 2004. J. Am. Chem. Soc. 126, 1590.
Product Information
CAS number671225-39-1
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₃H₁₆N₄O₂
Chemical formulaC₁₃H₁₆N₄O₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetDifferentiation of ESCs (embryonic stem cells) into cardiomyocytes
Primary Target IC<sub>50</sub>EC50 = 100 nM inducing the differentiation of ESCs (embryonic stem cells) into cardiomyocytes
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalogové číslo GTIN
217460 0

Documentation

Cardiogenol C - CAS 671225-39-1 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Cardiogenol C - CAS 671225-39-1 - Calbiochem Certificates of Analysis

TitleLot Number
217460

References

Přehled odkazů
Wu, X., et al. 2004. J. Am. Chem. Soc. 126, 1590.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-April-2011 RFH
Synonyms2-(4-Methoxyanilino)-4-(1-hydroxyethylamino)pyrimidine
DescriptionA cell-permeable pyrimidine compound that potently induces the differentiation of embryonic stem cells (ESCs) into cardiomyocytes (EC50 = 100 nM). Does not exhibit cytotoxic effects even at concentrations as high as 25 µM. The induction of cardiomyogenesis by Cardiogenol C is reported to be more efficient than that achieved by embryoid bodies (EBs) and DMSO treatment.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number671225-39-1
Chemical formulaC₁₃H₁₆N₄O₂
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (10 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Carcinogenic / Teratogenic
ReferencesWu, X., et al. 2004. J. Am. Chem. Soc. 126, 1590.