208293 Sigma-AldrichCalcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem
The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel.
More>> The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 6-tert-butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid, CaCC Blocker I, TMEM16 Blocker I, ANO Blocker I, Anoctamin Blocker I
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Přehled
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Tabulka spec. kláve
| CAS # | Empirical Formula |
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| 407587-33-1 | C₁₈H₂₁NO₄S |
Products
| Katalogové číslo | Balení | ks/bal. | |
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| 208293-10MG | Skleněná láhev | 10 mg |
| Description | |
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| Overview | An aminothiophene that inhibits Calcium-activated Chloride Channel (CaCC) current influx induced by multiple calcium-elevating agonists (IC50 = 10 µM) without inhibiting calcium elevation, and CaMKII and CFTR activity. Inhibits CaCC chloride response following agonist stimulation in human bronchial and intestinal epithelial cells. Also demonstrates an inhibitory effect on TMEM16A channels (IC50 = 2.1 µM). Also available as a 100 mM solution in DMSO (Cat. No. 508628). |
| Catalogue Number | 208293 |
| Brand Family | Calbiochem® |
| Synonyms | 6-tert-butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid, CaCC Blocker I, TMEM16 Blocker I, ANO Blocker I, Anoctamin Blocker I |
| References | |
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| References | Fuente, R., et al. 2011, Mol Pharmacol. 73, 758. Namkung, W., et al. 2011, J Biol Chem. 286, 2365. |
| Product Information | |
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| CAS number | 407587-33-1 |
| Form | Off-white solid |
| Hill Formula | C₁₈H₂₁NO₄S |
| Chemical formula | C₁₈H₂₁NO₄S |
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| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥98% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Katalogové číslo | GTIN |
| 208293-10MG | 04055977203264 |
Documentation
Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem MSDS
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Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 208293 |
References
| Přehled odkazů |
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| Fuente, R., et al. 2011, Mol Pharmacol. 73, 758. Namkung, W., et al. 2011, J Biol Chem. 286, 2365. |